Comparative metabolic and cardiovascular effects of carbuterol, isoproterenol, metaproterenol and salbutamol in the baboon

D. E. Potter, L. C. Woodson, R. R. Kempen, S. Ellis

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

The metabolic and cardiovascular responses to two bronchiolar selective β-adrenergic drugs in elevating plasma levels of glucose, lactate, free fatty acids, insulin, and glucagon. Moreover, ISO was more active in increasing heart rate and respiratory rate and in depressing diastolic blood pressure. Although ISO was shown to have greater activity than CAR, MET, and SAL, the bronchiolar selective drugs (CAR and SAL) did produce significant changes in plasma levels of metabolic substrates and pancreatic hormones and in cardiovascular measurements at higher dose rates.

Original languageEnglish (US)
Pages (from-to)323-327
Number of pages5
JournalHormone and Metabolic Research
Volume12
Issue number7
StatePublished - 1980

Fingerprint

Metaproterenol
Albuterol
Papio
Isoproterenol
Pancreatic Hormones
Blood Pressure
Plasmas
Blood pressure
Respiratory Rate
Glucagon
Nonesterified Fatty Acids
Adrenergic Agents
Lactic Acid
Heart Rate
Insulin
Glucose
Substrates
Pharmaceutical Preparations
carbuterol

ASJC Scopus subject areas

  • Biochemistry
  • Endocrinology

Cite this

Comparative metabolic and cardiovascular effects of carbuterol, isoproterenol, metaproterenol and salbutamol in the baboon. / Potter, D. E.; Woodson, L. C.; Kempen, R. R.; Ellis, S.

In: Hormone and Metabolic Research, Vol. 12, No. 7, 1980, p. 323-327.

Research output: Contribution to journalArticle

Potter, D. E. ; Woodson, L. C. ; Kempen, R. R. ; Ellis, S. / Comparative metabolic and cardiovascular effects of carbuterol, isoproterenol, metaproterenol and salbutamol in the baboon. In: Hormone and Metabolic Research. 1980 ; Vol. 12, No. 7. pp. 323-327.
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