Comparative metabolic and cardiovascular effects of carbuterol, isoproterenol, metaproterenol and salbutamol in the baboon

D. E. Potter, L. C. Woodson, R. R. Kempen, S. Ellis

    Research output: Contribution to journalArticle

    4 Scopus citations

    Abstract

    The metabolic and cardiovascular responses to two bronchiolar selective β-adrenergic drugs in elevating plasma levels of glucose, lactate, free fatty acids, insulin, and glucagon. Moreover, ISO was more active in increasing heart rate and respiratory rate and in depressing diastolic blood pressure. Although ISO was shown to have greater activity than CAR, MET, and SAL, the bronchiolar selective drugs (CAR and SAL) did produce significant changes in plasma levels of metabolic substrates and pancreatic hormones and in cardiovascular measurements at higher dose rates.

    Original languageEnglish (US)
    Pages (from-to)323-327
    Number of pages5
    JournalHormone and Metabolic Research
    Volume12
    Issue number7
    DOIs
    StatePublished - Jan 1 1980

    ASJC Scopus subject areas

    • Endocrinology, Diabetes and Metabolism
    • Biochemistry
    • Endocrinology
    • Clinical Biochemistry
    • Biochemistry, medical

    Fingerprint Dive into the research topics of 'Comparative metabolic and cardiovascular effects of carbuterol, isoproterenol, metaproterenol and salbutamol in the baboon'. Together they form a unique fingerprint.

  • Cite this