Comparative sequence analysis of the N-terminal region of rat, rabbit, and dog haptoglobin β-chains

Alexander Kurosky, Han Hwa Kim, Billy Touchstone

    Research output: Contribution to journalArticle

    23 Citations (Scopus)

    Abstract

    1. 1. Quantitative sequence analysis of a 40-residue segment of the amino-terminal region of the β-chain of haptoglobin isolated from sera of rat, rabbit, and dog was undertaken. 2. 2. All three haptoglobin β-chains aligned precisely with human β-chain with no evidence of deletions or insertions. 3. 3. The % difference in amino acid residues between the haptoglobin β-chains was comparable to that reported for the β-chains of hemoglobin from identical mammalian sources. 4. 4. Human and dog haptoglobin β-chains had carbohydrate attached to asparagine at residue-23 whereas rat and rabbit did not.

    Original languageEnglish
    Pages (from-to)453-459
    Number of pages7
    JournalComparative Biochemistry and Physiology -- Part B: Biochemistry and
    Volume55
    Issue number3
    DOIs
    StatePublished - 1976

    Fingerprint

    Haptoglobins
    Sequence Analysis
    Rats
    Dogs
    Rabbits
    Asparagine
    Hemoglobins
    Carbohydrates
    Amino Acids
    Serum

    ASJC Scopus subject areas

    • Medicine(all)

    Cite this

    Comparative sequence analysis of the N-terminal region of rat, rabbit, and dog haptoglobin β-chains. / Kurosky, Alexander; Kim, Han Hwa; Touchstone, Billy.

    In: Comparative Biochemistry and Physiology -- Part B: Biochemistry and, Vol. 55, No. 3, 1976, p. 453-459.

    Research output: Contribution to journalArticle

    @article{2527fbb932c6428095ec837dff42b836,
    title = "Comparative sequence analysis of the N-terminal region of rat, rabbit, and dog haptoglobin β-chains",
    abstract = "1. 1. Quantitative sequence analysis of a 40-residue segment of the amino-terminal region of the β-chain of haptoglobin isolated from sera of rat, rabbit, and dog was undertaken. 2. 2. All three haptoglobin β-chains aligned precisely with human β-chain with no evidence of deletions or insertions. 3. 3. The {\%} difference in amino acid residues between the haptoglobin β-chains was comparable to that reported for the β-chains of hemoglobin from identical mammalian sources. 4. 4. Human and dog haptoglobin β-chains had carbohydrate attached to asparagine at residue-23 whereas rat and rabbit did not.",
    author = "Alexander Kurosky and Kim, {Han Hwa} and Billy Touchstone",
    year = "1976",
    doi = "10.1016/0305-0491(76)90320-5",
    language = "English",
    volume = "55",
    pages = "453--459",
    journal = "Comparative biochemistry and physiology. B, Comparative biochemistry",
    issn = "0305-0491",
    publisher = "Elsevier BV",
    number = "3",

    }

    TY - JOUR

    T1 - Comparative sequence analysis of the N-terminal region of rat, rabbit, and dog haptoglobin β-chains

    AU - Kurosky, Alexander

    AU - Kim, Han Hwa

    AU - Touchstone, Billy

    PY - 1976

    Y1 - 1976

    N2 - 1. 1. Quantitative sequence analysis of a 40-residue segment of the amino-terminal region of the β-chain of haptoglobin isolated from sera of rat, rabbit, and dog was undertaken. 2. 2. All three haptoglobin β-chains aligned precisely with human β-chain with no evidence of deletions or insertions. 3. 3. The % difference in amino acid residues between the haptoglobin β-chains was comparable to that reported for the β-chains of hemoglobin from identical mammalian sources. 4. 4. Human and dog haptoglobin β-chains had carbohydrate attached to asparagine at residue-23 whereas rat and rabbit did not.

    AB - 1. 1. Quantitative sequence analysis of a 40-residue segment of the amino-terminal region of the β-chain of haptoglobin isolated from sera of rat, rabbit, and dog was undertaken. 2. 2. All three haptoglobin β-chains aligned precisely with human β-chain with no evidence of deletions or insertions. 3. 3. The % difference in amino acid residues between the haptoglobin β-chains was comparable to that reported for the β-chains of hemoglobin from identical mammalian sources. 4. 4. Human and dog haptoglobin β-chains had carbohydrate attached to asparagine at residue-23 whereas rat and rabbit did not.

    UR - http://www.scopus.com/inward/record.url?scp=0017201942&partnerID=8YFLogxK

    UR - http://www.scopus.com/inward/citedby.url?scp=0017201942&partnerID=8YFLogxK

    U2 - 10.1016/0305-0491(76)90320-5

    DO - 10.1016/0305-0491(76)90320-5

    M3 - Article

    C2 - 975782

    AN - SCOPUS:0017201942

    VL - 55

    SP - 453

    EP - 459

    JO - Comparative biochemistry and physiology. B, Comparative biochemistry

    JF - Comparative biochemistry and physiology. B, Comparative biochemistry

    SN - 0305-0491

    IS - 3

    ER -