Comparison of dehydrated human amnion-chorion and type 1 bovine collagen membranes in alveolar ridge preservation: A clinical and histological study

Samer A. Faraj, Ahmad Kutkut, Robert C. Taylor, Alejandro Villasante-Tezanos, Sarandeep S. Huja, Dolphus R. Dawson, Nehal Almehmadi, Mohanad Al-Sabbagh

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Alveolar ridge preservation maintains ridge dimensions and bone quality for implant placement. The aim of this randomized controlled clinical study is to compare the use of a human amnion-chorion membrane to a collagen membrane in an exposed-barrier ridge preservation technique. Furthermore, this study will determine if intentional membrane exposure compromises ridge dimensions and bone vitality. Forty-three patients requiring extraction and delayed implant placement were randomly assigned into either the experimental or control group. Twenty-one participants received human amnion-chorion membrane (test) during ridge preservation while 22 participants received the collagen membrane (control). In both groups, demineralized freeze-dried bone allografts were used to graft the socket and primary closure was not achieved. The patients underwent implant placement after an average healing period of 19.5 weeks, and 2.7 3 8-mm core bone specimens were obtained for histomorphometric analyses. The clinical ridge dimensions were measured after extraction and at the time of delayed implant placement. No significant difference was observed in the mean vital bone formation between the experimental (51.72 6 8.46%) and control (49.96 6 8.31%; P . .05) groups. The bone height and width did not differ, as determined by clinical measurements (P . .05). Using either a human amnion-chorion membrane or type 1 bovine collagen as the open barrier did not change healing, compromise ridge dimensions, or affect bone vitality between the 2 groups.

Original languageEnglish (US)
Pages (from-to)385-393
Number of pages9
JournalJournal of Oral Implantology
Volume47
Issue number5
DOIs
StatePublished - Oct 2021
Externally publishedYes

Keywords

  • Amnion-chorion membrane
  • Collagen membrane
  • Resorbable membrane
  • Ridge preservation

ASJC Scopus subject areas

  • Oral Surgery

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