Comparison of optoacoustic tomography with ultrasound and X-ray imaging for breast cancer detection

K. Larin, O. Hartrumpf, I. Larina, Rinat Esenaliev

Research output: Chapter in Book/Report/Conference proceedingConference contribution

11 Citations (Scopus)

Abstract

This paper is devoted to comparison new optoacoustic tomography with conventional breast tumors diagnostic techniques such as ultrasonography and X-ray radiography. Experiments were performed in phantoms simulating breast with tumors. The fundamental harmonic of Q-switched Nd:YAG laser (λ = 1064 nm) was used to generate optoacoustic pressure waves. Laser induced pressure waves were detected by a wide-band acoustic transducer. Digital oscilloscope controlled by PC was used to store and process optoacoustic signals. Gelatin phantoms with controlled optical parameters were prepared to simulate breast with tumors. Absorbing volumes colored with naphthol green and hemoglobin were embedded in the gelatin phantoms to model the breast tumors with increased optical absorption. Optoacoustic pressure waves from the phantoms were detected at different angles and 2D images were reconstructed. Comparison of optoacoustic images with images obtained with ultrasound and X-ray techniques proved that optoacoustic method has substantially higher contrast and resolution. Obtained results confirm that laser optoacoustic imaging technique can be an important tool for early breast cancer detection with tumors less than 5 mm in diameter.

Original languageEnglish (US)
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
EditorsA.A. Oraevsky
Pages147-153
Number of pages7
Volume4256
DOIs
StatePublished - 2001
EventBiomedical Optoacoustics II - San Jose, CA, United States
Duration: Jan 23 2001Jan 24 2001

Other

OtherBiomedical Optoacoustics II
CountryUnited States
CitySan Jose, CA
Period1/23/011/24/01

Fingerprint

Photoacoustic effect
breast
Tomography
tumors
tomography
Ultrasonics
cancer
Imaging techniques
X rays
Tumors
elastic waves
gelatins
x rays
Lasers
oscilloscopes
hemoglobin
Q switched lasers
radiography
X ray radiography
Acoustic transducers

Keywords

  • Breast cancer
  • Imaging
  • Noninvasive
  • Optoacoustics

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Condensed Matter Physics

Cite this

Larin, K., Hartrumpf, O., Larina, I., & Esenaliev, R. (2001). Comparison of optoacoustic tomography with ultrasound and X-ray imaging for breast cancer detection. In A. A. Oraevsky (Ed.), Proceedings of SPIE - The International Society for Optical Engineering (Vol. 4256, pp. 147-153) https://doi.org/10.1117/12.429301

Comparison of optoacoustic tomography with ultrasound and X-ray imaging for breast cancer detection. / Larin, K.; Hartrumpf, O.; Larina, I.; Esenaliev, Rinat.

Proceedings of SPIE - The International Society for Optical Engineering. ed. / A.A. Oraevsky. Vol. 4256 2001. p. 147-153.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Larin, K, Hartrumpf, O, Larina, I & Esenaliev, R 2001, Comparison of optoacoustic tomography with ultrasound and X-ray imaging for breast cancer detection. in AA Oraevsky (ed.), Proceedings of SPIE - The International Society for Optical Engineering. vol. 4256, pp. 147-153, Biomedical Optoacoustics II, San Jose, CA, United States, 1/23/01. https://doi.org/10.1117/12.429301
Larin K, Hartrumpf O, Larina I, Esenaliev R. Comparison of optoacoustic tomography with ultrasound and X-ray imaging for breast cancer detection. In Oraevsky AA, editor, Proceedings of SPIE - The International Society for Optical Engineering. Vol. 4256. 2001. p. 147-153 https://doi.org/10.1117/12.429301
Larin, K. ; Hartrumpf, O. ; Larina, I. ; Esenaliev, Rinat. / Comparison of optoacoustic tomography with ultrasound and X-ray imaging for breast cancer detection. Proceedings of SPIE - The International Society for Optical Engineering. editor / A.A. Oraevsky. Vol. 4256 2001. pp. 147-153
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