Comparison of parenteral nutrition and enteral feeding with pectin in experimental colitis in the rat

R. H. Rolandelli, S. H. Saul, R. G. Settle, D. O. Jacobs, S. O. Trerotola, J. L. Rombeau

Research output: Contribution to journalArticle

40 Citations (Scopus)

Abstract

The effect of a pectin-supplemented enteral diet on experimental colitis was compared with parenteral nutrition and with a pectin-free enteral diet. Forty-five rats had feeding catheters placed into either the stomach (IG, n=31) or the superior vena cava (IV, n=14) and then received acetic acid (colitis) or saline (control) enemas. After the enema, all rats received the same diet, either IG or IV, for 6 d except for 15 rats (IGP, 9 colitis and 6 controls), which had 1% pectin added to the diet. At the end of the feeding period the IGP group had significantly less colonic inflammation and/or necrosis than either IV (p<0.03) or IG (p<0.04) groups. Nitrogen balance, serum albumin, total iron-binding capacity and body weight did not differ significantly among dietary regimens. Thus, the degree of bowel injury in experimental colitis was decreased when animals were fed a pectin-supplemented enteral diet and this effect was independent of nutritional status.

Original languageEnglish (US)
Pages (from-to)715-721
Number of pages7
JournalAmerican Journal of Clinical Nutrition
Volume47
Issue number4
StatePublished - 1988
Externally publishedYes

Fingerprint

Parenteral Nutrition
colitis
enteral feeding
Enteral Nutrition
parenteral feeding
Colitis
pectins
Diet
rats
Small Intestine
Enema
superior vena cava
binding capacity
serum albumin
nitrogen balance
catheters
diet
Superior Vena Cava
acetic acid
nutritional status

ASJC Scopus subject areas

  • Food Science
  • Medicine (miscellaneous)

Cite this

Rolandelli, R. H., Saul, S. H., Settle, R. G., Jacobs, D. O., Trerotola, S. O., & Rombeau, J. L. (1988). Comparison of parenteral nutrition and enteral feeding with pectin in experimental colitis in the rat. American Journal of Clinical Nutrition, 47(4), 715-721.

Comparison of parenteral nutrition and enteral feeding with pectin in experimental colitis in the rat. / Rolandelli, R. H.; Saul, S. H.; Settle, R. G.; Jacobs, D. O.; Trerotola, S. O.; Rombeau, J. L.

In: American Journal of Clinical Nutrition, Vol. 47, No. 4, 1988, p. 715-721.

Research output: Contribution to journalArticle

Rolandelli, RH, Saul, SH, Settle, RG, Jacobs, DO, Trerotola, SO & Rombeau, JL 1988, 'Comparison of parenteral nutrition and enteral feeding with pectin in experimental colitis in the rat', American Journal of Clinical Nutrition, vol. 47, no. 4, pp. 715-721.
Rolandelli RH, Saul SH, Settle RG, Jacobs DO, Trerotola SO, Rombeau JL. Comparison of parenteral nutrition and enteral feeding with pectin in experimental colitis in the rat. American Journal of Clinical Nutrition. 1988;47(4):715-721.
Rolandelli, R. H. ; Saul, S. H. ; Settle, R. G. ; Jacobs, D. O. ; Trerotola, S. O. ; Rombeau, J. L. / Comparison of parenteral nutrition and enteral feeding with pectin in experimental colitis in the rat. In: American Journal of Clinical Nutrition. 1988 ; Vol. 47, No. 4. pp. 715-721.
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