Comparison of somatostatin and pancreastatin on secretion of gastrin, pancreatic polypeptide, and peptide YY

Guillermo Gomez, Vidyavathi Udupi, George H Greeley

Research output: Contribution to journalArticle

5 Scopus citations

Abstract

The purpose of this study was to compare the effects of pancreastatin (PST) (400 pmol/kg/hr) end somatostatin (SRIF) (400 pmol/kg/hr) on food- induced release of gastrin, pancreatic polypeptide (PP), and peptide YY (PYY) in conscious dogs. The present findings indicate that SRIF is more potent than PST on the inhibition of food-induced release of PP; that SRIF and PST do not influence food-induced release of gastrin; and that PST cannot inhibit food-induced release of PYY, whereas SRIF inhibits PYY release in a potent fashion.

Original languageEnglish (US)
Pages (from-to)165-167
Number of pages3
JournalProceedings of the Society for Experimental Biology and Medicine
Volume215
Issue number2
DOIs
StatePublished - Jun 1997

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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