TY - JOUR
T1 - Comparison of three rapid diagnostic techniques for detection of respiratory syncytial virus from nasal wash specimens
AU - Chonmaitree, T.
AU - Bessette-Henderson, B. J.
AU - Hepler, R. E.
AU - Lucia, H. L.
PY - 1987
Y1 - 1987
N2 - We report results of three rapid tests for respiratory syncytial virus antigen detection. An immunofluorescence assay using commercial antibody and two commercial enzyme immunoassays (Ortho Diagnostics, Inc., Raritan, N.J., and Abbott Laboratories, North Chicago, Ill.) were applied to 199 nasal wash specimens. The Abbott enzyme immunoassay was the most sensitive technique, with a sensitivity of 93.8%. The specificities of the three techniques were comparable and greater than 95%. The availability of reliable rapid diagnostic techniques will allow for better care of infants with severe respiratory syncytial virus infection.
AB - We report results of three rapid tests for respiratory syncytial virus antigen detection. An immunofluorescence assay using commercial antibody and two commercial enzyme immunoassays (Ortho Diagnostics, Inc., Raritan, N.J., and Abbott Laboratories, North Chicago, Ill.) were applied to 199 nasal wash specimens. The Abbott enzyme immunoassay was the most sensitive technique, with a sensitivity of 93.8%. The specificities of the three techniques were comparable and greater than 95%. The availability of reliable rapid diagnostic techniques will allow for better care of infants with severe respiratory syncytial virus infection.
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U2 - 10.1128/jcm.25.4.746-747.1987
DO - 10.1128/jcm.25.4.746-747.1987
M3 - Article
C2 - 3553236
AN - SCOPUS:0023138427
SN - 0095-1137
VL - 25
SP - 746
EP - 747
JO - Journal of Clinical Microbiology
JF - Journal of Clinical Microbiology
IS - 4
ER -