Comparison of three rapid diagnostic techniques for detection of respiratory syncytial virus from nasal wash specimens

T. Chonmaitree, B. J. Bessette-Henderson, R. E. Hepler, H. L. Lucia

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

We report results of three rapid tests for respiratory syncytial virus antigen detection. An immunofluorescence assay using commercial antibody and two commercial enzyme immunoassays (Ortho Diagnostics, Inc., Raritan, N.J., and Abbott Laboratories, North Chicago, Ill.) were applied to 199 nasal wash specimens. The Abbott enzyme immunoassay was the most sensitive technique, with a sensitivity of 93.8%. The specificities of the three techniques were comparable and greater than 95%. The availability of reliable rapid diagnostic techniques will allow for better care of infants with severe respiratory syncytial virus infection.

Original languageEnglish (US)
Pages (from-to)746-747
Number of pages2
JournalJournal of Clinical Microbiology
Volume25
Issue number4
StatePublished - 1987

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Respiratory Syncytial Viruses
Immunoenzyme Techniques
Nose
Infant Care
Respiratory Syncytial Virus Infections
Fluorescent Antibody Technique
Antigens
Antibodies

ASJC Scopus subject areas

  • Microbiology
  • Microbiology (medical)

Cite this

Chonmaitree, T., Bessette-Henderson, B. J., Hepler, R. E., & Lucia, H. L. (1987). Comparison of three rapid diagnostic techniques for detection of respiratory syncytial virus from nasal wash specimens. Journal of Clinical Microbiology, 25(4), 746-747.

Comparison of three rapid diagnostic techniques for detection of respiratory syncytial virus from nasal wash specimens. / Chonmaitree, T.; Bessette-Henderson, B. J.; Hepler, R. E.; Lucia, H. L.

In: Journal of Clinical Microbiology, Vol. 25, No. 4, 1987, p. 746-747.

Research output: Contribution to journalArticle

Chonmaitree, T, Bessette-Henderson, BJ, Hepler, RE & Lucia, HL 1987, 'Comparison of three rapid diagnostic techniques for detection of respiratory syncytial virus from nasal wash specimens', Journal of Clinical Microbiology, vol. 25, no. 4, pp. 746-747.
Chonmaitree, T. ; Bessette-Henderson, B. J. ; Hepler, R. E. ; Lucia, H. L. / Comparison of three rapid diagnostic techniques for detection of respiratory syncytial virus from nasal wash specimens. In: Journal of Clinical Microbiology. 1987 ; Vol. 25, No. 4. pp. 746-747.
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