■ BACKGROUND AND OBJECTIVE: To compare the intraobserver and interobserver agreement of anterior chamber angle measurements using unenhanced and enhanced imaging protocols for anterior segment optical coherence tomography (AS-OCT). ■ PATIENTS AND METHODS: Anterior segments of 30 eyes of 15 healthy subjects (mean age: 33.8 ± 13.0 years, 8 women) were imaged by a single examiner with AS-OCT using unenhanced and enhanced imaging protocol. Two masked observers analyzed each image independently on two separate occasions. The reproducibility of angle parameters was estimated by calculating coefficients of variation separately for each observer. Bland-Altman plots were constructed to assess the intraobserver and interobserver agreement. ■ RESULTS: The intraobserver and interobserver reproducibility was similar between imaging protocols. Intra-observer and interobserver agreements were also similar for all parameters evaluated. The best estimate of scleral spur location was determined in all images by both observers. ■ CONCLUSION: Measurement variability was similar with the unenhanced and enhanced imaging protocol in this series of eyes with open angles.
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