Complete hydatidiform mole and live fetus in a singleton pregnancy with confined placental mosaicism and fetomaternal hemorrhage: A case report

Laxmi V. Baxi, Mahesh Mansukhani, Harshwardhan Thaker, Elvira Parravicini

Research output: Contribution to journalArticle

2 Scopus citations

Abstract

BACKGROUND: Coexistence of complete mole and a live fetus is uncommon (1:22,000–100,000), more so with euploidy. CASE: We present a case of a molar pregnancy with a euploid fetus who had close fetal evaluation for second trimester bleeding. The patient presented at 29 weeks’ gestation with decreased fetal movements, a result of fetomaternal hemorrhage. She underwent emergency cesarean section and delivered a live infant. By close followup and a multidisciplinary approach, the appropriate diagnosis and a favorable outcome were achieved. Both mother and the child at 5 years of age are doing well. CONCLUSION: Detailed anatomic and molecular studies demonstrated a complete mole resulting from confined placental mosaicism, with molar tissue showing a single paternal allele at 8/8 informative loci, all shared with the fetus, thus this coexistent molar pregnancy was not that of a separate conceptus.

Original languageEnglish (US)
Pages (from-to)599-602
Number of pages4
JournalJournal of Reproductive Medicine
Volume59
Issue number6
StatePublished - Dec 1 2014
Externally publishedYes

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Keywords

  • Confined placental mosaicism
  • Fetomaternal hemorrhage
  • Hydatidiform mole
  • Molar pregnancy
  • Molar pregnancy with coexisting live newborn

ASJC Scopus subject areas

  • Reproductive Medicine
  • Obstetrics and Gynecology

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