COMPRES: A prospective postmarketing evaluation of the compression anastomosis ring CAR 27/ColonRing

A. D'Hoore, M. R. Albert, S. M. Cohen, F. Herbst, I. Matter, K. Van Der Speeten, J. Dominguez, H. Rutten, J. P. Muldoon, O. Bardakcioglu, A. J. Senagore, R. Ruppert, S. Mills, M. J. Stamos, L. Påhlman, E. Choman, S. D. Wexner, behalf of the COMPRES collaborative study group On behalf of the COMPRES collaborative study group

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

Aim: Preclinical studies have suggested that nitinol-based compression anastomosis might be a viable solution to anastomotic leak following low anterior resection. A prospective multicentre open label study was therefore designed to evaluate the performance of the ColonRing in (low) colorectal anastomosis. Method: The primary outcome measure was anastomotic leakage. Patients were recruited at 13 different colorectal surgical units in Europe, the United States and Israel. Institutional review board approval was obtained. Results: Between 21 March 2010 and 3 August 2011, 266 patients completed the study protocol. The overall anastomotic leakage rate was 5.3% for all anastomoses, including a rate of 3.1% for low anastomoses. Septic anastomotic complications occurred in 8.3% of all anastomoses and 8.2% of low anastomoses. Conclusion: Nitinol compression anastomosis is safe, effective and easy to use and may offer an advantage for low colorectal anastomosis. A prospective randomized trial comparing ColonRing with conventional stapling is needed. Copyright

Original languageEnglish (US)
Pages (from-to)522-529
Number of pages8
JournalColorectal Disease
Volume17
Issue number6
DOIs
StatePublished - Jun 1 2015
Externally publishedYes

Keywords

  • Anastomotic leakage
  • Compression anastomosis
  • Low anterior resection

ASJC Scopus subject areas

  • Gastroenterology

Fingerprint

Dive into the research topics of 'COMPRES: A prospective postmarketing evaluation of the compression anastomosis ring CAR 27<sup>™</sup>/ColonRing<sup>™</sup>'. Together they form a unique fingerprint.

Cite this