COMPRES: A prospective postmarketing evaluation of the compression anastomosis ring CAR 27/ColonRing

A. D'Hoore, M. R. Albert, S. M. Cohen, F. Herbst, I. Matter, K. Van Der Speeten, J. Dominguez, H. Rutten, J. P. Muldoon, O. Bardakcioglu, A. J. Senagore, R. Ruppert, S. Mills, M. J. Stamos, L. Påhlman, E. Choman, S. D. Wexner, behalf of the COMPRES collaborative study group On behalf of the COMPRES collaborative study group

    Research output: Contribution to journalArticle

    11 Scopus citations

    Abstract

    Aim: Preclinical studies have suggested that nitinol-based compression anastomosis might be a viable solution to anastomotic leak following low anterior resection. A prospective multicentre open label study was therefore designed to evaluate the performance of the ColonRing in (low) colorectal anastomosis. Method: The primary outcome measure was anastomotic leakage. Patients were recruited at 13 different colorectal surgical units in Europe, the United States and Israel. Institutional review board approval was obtained. Results: Between 21 March 2010 and 3 August 2011, 266 patients completed the study protocol. The overall anastomotic leakage rate was 5.3% for all anastomoses, including a rate of 3.1% for low anastomoses. Septic anastomotic complications occurred in 8.3% of all anastomoses and 8.2% of low anastomoses. Conclusion: Nitinol compression anastomosis is safe, effective and easy to use and may offer an advantage for low colorectal anastomosis. A prospective randomized trial comparing ColonRing with conventional stapling is needed. Copyright

    Original languageEnglish (US)
    Pages (from-to)522-529
    Number of pages8
    JournalColorectal Disease
    Volume17
    Issue number6
    DOIs
    StatePublished - Jun 1 2015

    Keywords

    • Anastomotic leakage
    • Compression anastomosis
    • Low anterior resection

    ASJC Scopus subject areas

    • Gastroenterology

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    D'Hoore, A., Albert, M. R., Cohen, S. M., Herbst, F., Matter, I., Van Der Speeten, K., Dominguez, J., Rutten, H., Muldoon, J. P., Bardakcioglu, O., Senagore, A. J., Ruppert, R., Mills, S., Stamos, M. J., Påhlman, L., Choman, E., Wexner, S. D., & On behalf of the COMPRES collaborative study group, B. O. T. COMPRES. C. S. G. (2015). COMPRES: A prospective postmarketing evaluation of the compression anastomosis ring CAR 27/ColonRing. Colorectal Disease, 17(6), 522-529. https://doi.org/10.1111/codi.12884