Consensus recommendations on the use of 18F-FDG PET/CT in lung disease

Delphine L. Chen, Safia Ballout, Laigao Chen, Joseph Cheriyan, Gourab Choudhury, Ana M. Denis-Bacelar, Elise Emond, Kjell Erlandsson, Marie Fisk, Francesco Fraioli, Ashley M. Groves, Roger N. Gunn, Jun Hatazawa, Beverley F. Holman, Brian F. Hutton, Hidehiro Iida, Sarah Lee, William MacNee, Keiko Matsunaga, Divya MohanDavid Parr, Alaleh Rashidnasab, Gaia Rizzo, Deepak Subramanian, Ruth Tal-Singer, Kris Thielemans, Nicola Tregay, Edwin J.R. van Beek, Laurence Vass, Marcos F. Vidal Melo, Jeremy W. Wellen, Ian Wilkinson, Frederick J. Wilson, Tilo Winkler

Research output: Contribution to journalArticlepeer-review

12 Scopus citations

Abstract

PET with 18F-FDG has been increasingly applied, predominantly in the research setting, to study drug effects and pulmonary biology and to monitor disease progression and treatment outcomes in lung diseases that interfere with gas exchange through alterations of the pulmonary parenchyma, airways, or vasculature. To date, however, there are no widely accepted standard acquisition protocols or imaging data analysis methods for pulmonary 18F-FDG PET/CT in these diseases, resulting in disparate approaches. Hence, comparison of data across the literature is challenging. To help harmonize the acquisition and analysis and promote reproducibility, we collated details of acquisition protocols and analysis methods from 7 PET centers. From this information and our discussions, we reached the consensus recommendations given here on patient preparation, choice of dynamic versus static imaging, image reconstruction, and image analysis reporting.

Original languageEnglish (US)
Pages (from-to)1701-1707
Number of pages7
JournalJournal of Nuclear Medicine
Volume61
Issue number12
DOIs
StatePublished - Dec 1 2020
Externally publishedYes

Keywords

  • FDG
  • Lung disease
  • PET/CT
  • Pulmonary imaging

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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