Construction of stable reporter flaviviruses and their applications

Coleman Baker; Pei Yong Shi

doi:10.3390/v12101082

Construction of stable reporter flaviviruses and their applications

Coleman Baker, Pei Yong Shi

Biochemistry & Molecular Biology

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Abstract

Flaviviruses are significant human pathogens that cause frequent emerging and reemerging epidemics around the world. Better molecular tools for studying, diagnosing, and treating these diseases are needed. Reporter viruses represent potent tools to fill this gap but have been hindered by genetic instability. Recent advances have overcome these hurdles, opening the way for increased use of stable reporter flaviviruses to diagnose infections, screen and study antiviral compounds, and serve as potential vaccine vectors.

Original language	English (US)
Article number	1082
Journal	Viruses
Volume	12
Issue number	10
DOIs	https://doi.org/10.3390/v12101082
State	Published - Oct 2020

Keywords

Emerging viruses
RNA
RNA viruses
Reporter viruses
Zoonosis

ASJC Scopus subject areas

Infectious Diseases
Virology

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10.3390/v12101082

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KW - Zoonosis

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Construction of stable reporter flaviviruses and their applications

Abstract

Keywords

ASJC Scopus subject areas

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