Control and Eradication of Human and Animal Diseases by Vaccination

Nigel Bourne, Gregg N. Milligan

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Abstract

For pathogens that infect only a single or a limited number of host species and for which effective vaccines are available, it is theoretically possible to eradicate the pathogen through immunization. The implementation of vigorous immunization programs in the 1960s and 1970s resulted in the eradication of the human pathogen smallpox virus in 1980. More recently, the veterinary pathogen rinderpest virus has also been eradicated as a result of intensive immunization and surveillance programs. This chapter outlines the characteristics of the pathogens that can be targeted for eradication and the strategies employed in the immunization programs responsible for successful eradication efforts. It also examines the difficulties encountered and new strategies for similar vaccination programs to eradicate other human and livestock pathogens.

Original languageEnglish (US)
Title of host publicationVaccinology
Subtitle of host publicationAn Essential Guide
PublisherWiley-Blackwell
Pages43-58
Number of pages16
ISBN (Electronic)9781118638033
ISBN (Print)9780470656167
DOIs
StatePublished - Dec 9 2014

Keywords

  • Control
  • Eradication
  • Foot-and-mouth disease
  • Herd immunity
  • Measles
  • Polio
  • Rinderpest virus
  • Smallpox

ASJC Scopus subject areas

  • General Medicine

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