Control and non-progression of HIV-1 infection in sub-Saharan Africa: A case and review

Premal Patel, M. Brooks, G. Anabwani, M. A. Tolle

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Elite and viraemic controllers represent unique subsets of HIV-infected patients who may also be long-term nonprogressors (LTNPs). LNTPs constitute an estimated 1 - 15% of the total HIV-positive population in the USA and Europe, but less is known about their epidemiology in sub-Saharan Africa. Though the exact mechanisms for long-term non-progression appear to be numerous and are still under investigation, research on elite controllers may hold the key to new therapeutics and vaccine development. The clinical management of such patients can be challenging, as there are no standard guidelines for treatment, particularly in resource-limited settings. We describe the case of an HIV-infected Botswanan man who is likely an elite or viraemic controller.

Original languageEnglish
Pages (from-to)152-155
Number of pages4
JournalSouthern African Journal of HIV Medicine
Volume13
Issue number3
DOIs
StatePublished - Sep 2012
Externally publishedYes

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Africa South of the Sahara
HIV Infections
HIV-1
HIV
Epidemiology
Vaccines
Guidelines
Therapeutics
Research
Population

ASJC Scopus subject areas

  • Infectious Diseases

Cite this

Control and non-progression of HIV-1 infection in sub-Saharan Africa : A case and review. / Patel, Premal; Brooks, M.; Anabwani, G.; Tolle, M. A.

In: Southern African Journal of HIV Medicine, Vol. 13, No. 3, 09.2012, p. 152-155.

Research output: Contribution to journalArticle

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