Conversion of PtdIns(4, 5)P₂ into PtdIns(5)P by the S.flexneri effector IpgD reorganizes host cell morphology

Keyphrases

• Host Cell 100%
• Cell Morphology 100%
• Phosphatidylinositol 100%
• Shigella Flexneri 100%
• 5′-monophosphate 100%
• PtdIns(4,5)P2 100%
• IpgD 100%
• Virulence Factors 33%
• Entry Site 33%
• Epithelial Cells 33%
• Phosphatase 33%
• Morphological Changes 33%
• Cellular Events 33%
• Eukaryotic Cells 33%
• Translocated 33%
• Actin Cytoskeleton Organization 33%
• Membrane Ruffling 33%
• Dephosphorylate 33%
• Pathogenic Bacteria 33%
• Phosphatidylinositol 4,5-bisphosphate (PIP2) 33%
• Inositol 33%
• Membrane Blebbing 33%
• Gram-negative Pathogens 33%
• Actin Filaments 33%
• Phosphoinositides 33%
• Tether Force 33%
• Membrane Tethering 33%

Biochemistry, Genetics and Molecular Biology

• Phosphatidylinositol 100%
• Actin 66%
• Morphology 33%
• Infectious Agent 33%
• Virulence Factor 33%
• Transfection 33%
• Cytoskeleton 33%
• Shigella flexneri 33%
• Phosphatidylinositol 4,5-bisphosphate 33%
• Phosphoinositide 33%
• Blebbing 33%
• Phosphatase 33%
• Inositol 33%

Pharmacology, Toxicology and Pharmaceutical Science

• Phosphatidylinositol 100%
• Actin 66%
• Infection 33%
• Infectious Agent 33%
• Virulence Factor 33%
• Inositol 33%
• Phosphatidylinositol 4,5 Bisphosphate 33%
• Shigella flexneri 33%
• Phosphatidylinositide 33%
• Phosphatase 33%