Core antigen mutations of human hepatitis B virus in hepatomas accumulate in MHC class II-restricted T cell epitopes

Keyphrases

• MHC Class II 100%
• Hepatoblastoma 100%
• Hepatitis B Virus 100%
• Human Hepatitis B Virus 100%
• Core Antigen 100%
• T-cell Epitope 100%
• Hepatitis B Virus DNA 66%
• Liver-derived 66%
• Liver 33%
• Concomitant mutation 33%
• Polymorphism 33%
• Structural Difference 33%
• Naturally Occurring mutations 33%
• Persistent Infection 33%
• Epitope 33%
• Mutation Frequency 33%
• Virus Genome 33%
• Molecular Information 33%
• No Significant Difference 33%
• Core Protein 33%
• Genetic Heterogeneity 33%
• Cytotoxic T Lymphocytes 33%
• Bona Fide 33%
• Escape mutation 33%
• HLA Class II 33%
• Liver Tumor 33%
• Core Genes 33%
• HLA Class I 33%
• Frequency Occurrence 33%
• Immunoevasion 33%
• Acute Hepatitis B 33%
• Hepatitis B Virus Core Antigen 33%
• Evolutionarily Conserved 33%
• I(V) 33%
• Chronic Hepatitis B Patients 33%
• Chronic Carrier 33%
• Conserved Position 33%

Immunology and Microbiology

• T Cell 100%
• Epitope 100%
• Antigen 100%
• Hepatitis B Virus 100%
• MHC Class II 100%
• Virus Core 30%
• DNA Virus 20%
• Wild Type 10%
• Virus Genome 10%
• Infectious Disease 10%
• Cytotoxic T Cell 10%
• Virus Nucleocapsid 10%
• Mutation Rate 10%
• Hepatitis B 10%
• Genetic Heterogeneity 10%
• Infection 10%