Corneal Scheimpflug Densitometry in Photorefractive Keratectomy Candidates

Mojgan Pakbin, Mehdi Khabazkhoob, Mohammad Pakravan, Akbar Fotouhi, Ebrahim Jafarzadehpur, Mohamadreza Aghamirsalim, Hassan Hashemi

Research output: Contribution to journalArticlepeer-review

14 Scopus citations


Purpose:To describe the normative data of corneal densitometry in photorefractive Keratectomy (PRK) candidates by using a Scheimpflug camera.Methods:Five hundred twenty-two eyes of 261 PRK candidates that underwent comprehensive optometric and ophthalmic examinations were enrolled in this study. Corneal densitometry values were obtained using a Scheimpflug camera (Pentacam HR; Oculus Optikgeräte GmbH, Wetzlar, Germany) and displayed in grayscale units (GSU).Results:Of 261 participants, 187 (71.6%) were women. The mean age of the participants was 28.79 ± 5.02 years (range: 21-40 years). The mean entire corneal densitometry was 14.86 ± 2.37 GSU. According to corneal depth, maximum and minimum densitometry values were seen in the anterior (30.28 ± 7.42 GSU) and posterior (9.86 ± 2.08 GSU) layers, respectively (P < 0.001). Based on the annulus over the cornea, the highest and lowest densitometry values were seen in the 10- to 12-mm (21.31 ± 4.26 GSU) and 2- to 6-mm zones (13.26 ± 2.34 GSU), respectively. However, this difference was not seen after 35 years of age. Individuals aged 30 to 35 years showed higher corneal densitometry values compared with subjects aged 20 to 25 years old (P < 0.001). In generalized linear models, the corneal thickness was associated with the densitometry value in the central and posterior corneal layers. There were no significant differences in sex and refractive errors among participants.Conclusions:This study provided normal corneal densitometry data in PRK candidates. Corneal densitometry increased with age until 35 years of age and then decreased thereafter. This finding should be considered in patient selection for PRK and their postoperative examinations.

Original languageEnglish (US)
Pages (from-to)1381-1388
Number of pages8
Issue number11
StatePublished - Nov 1 2020
Externally publishedYes


  • Pentacam
  • Scheimpflug camera
  • corneal densitometry
  • photorefractive keratometry

ASJC Scopus subject areas

  • Ophthalmology


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