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Correction: The formation of tau pore-like structures is prevalent and cell specific: possible implications for the disease phenotypes (Acta Neuropathologica Communications, (2014), 2, 1, (56), 10.1186/2051-5960-2-56)

  • Cristian A. Lasagna-Reeves
  • , Urmi Sengupta
  • , Diana Castillo-Carranza
  • , Julia E. Gerson
  • , Marcos Guerrero-Munoz
  • , Juan C. Troncoso
  • , George R. Jackson
  • , Rakez Kayed

Research output: Contribution to journalComment/debatepeer-review

Abstract

In this article, Fig. 2 appeared incorrectly and have now been corrected in the original publication. For completeness and transparency, both correct and incorrect versions are displayed below. The original article has been corrected. Incorrect Figure: Tau APFs are present in DLB and PSP brain tissue. The age, gender, post-mortem interval (PMI), and sampled brain regions in each group is summa-rized (a). APFs were detected in DLB cortex (top panel) and PSP pons (bottom panel) by light field microscopy after immunolabeling with αAPF (b). After immunoprecipitation using αAPF, tau annular structures were detected in DLB and PSP cases but not in age-matched control brain tissue (top, cortex; bottom, pons) by dot-blot analysis using Tau-5 antibody (c). Tau amyloid pores isolated from DLB (top) and PSP (bottom) brain tissue were visualized by AFM (d). Scale bar for HRP staining, 10 μm. Scale bar for AFM images, 30 nm. White arrowheads indicate tau APFs Correct Figure: (Figure presented.) Tau APFs are present in DLB and PSP brain tissue. The age, gender, post-mortem interval (PMI), and sampled brain regions in each group is summarized (a). APFs were detected in DLB cortex (top panel) and PSP pons (bottom panel) by light field microscopy after immunolabeling with αAPF (b). After immunoprecipitation using αAPF, tau annular structures were detected in DLB and PSP cases but not in age-matched control brain tissue (top, cortex; bottom, pons) by dot-blot analysis using Tau-5 antibody (c). Tau amyloid pores isolated from DLB (top) and PSP (bottom) brain tissue were visualized by AFM (d). Scale bar for HRP staining, 10 μm. Scale bar for AFM images, 30 nm.

Original languageEnglish (US)
Article number82
JournalActa Neuropathologica Communications
Volume14
Issue number1
DOIs
StatePublished - Dec 2026

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Clinical Neurology
  • Cellular and Molecular Neuroscience

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