Correlation of severity of human tick-borne encephalitis virus disease and pathogenicity in mice

Chaitanya Kurhade; Sarah Schreier; Yi Ping Lee; Loreen Zegenhagen; Marika Hjertqvist; Gerhard Dobler; Andrea Kröger; Anna K. Överby

doi:10.3201/eid2409.171825

Correlation of severity of human tick-borne encephalitis virus disease and pathogenicity in mice

Chaitanya Kurhade, Sarah Schreier, Yi Ping Lee, Loreen Zegenhagen, Marika Hjertqvist, Gerhard Dobler, Andrea Kröger, Anna K. Överby

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Abstract

We compared 2 tick-borne encephalitis virus strains isolated from 2 different foci that cause different symptoms in tick-borne encephalitis patients, from neurologic to mild gastrointestinal symptoms. We compared neuroinvasiveness, neurovirulence, and proinflammatory cytokine response in mice and found unique differences that contribute to our understanding of pathogenesis.

Original language	English (US)
Pages (from-to)	1709-1712
Number of pages	4
Journal	Emerging infectious diseases
Volume	24
Issue number	9
DOIs	https://doi.org/10.3201/eid2409.171825
State	Published - Sep 2018
Externally published	Yes

ASJC Scopus subject areas

Epidemiology
Microbiology (medical)
Infectious Diseases

Access to Document

10.3201/eid2409.171825

Cite this

@article{2d245579a31b46c6b22f58027f856132,

title = "Correlation of severity of human tick-borne encephalitis virus disease and pathogenicity in mice",

abstract = "We compared 2 tick-borne encephalitis virus strains isolated from 2 different foci that cause different symptoms in tick-borne encephalitis patients, from neurologic to mild gastrointestinal symptoms. We compared neuroinvasiveness, neurovirulence, and proinflammatory cytokine response in mice and found unique differences that contribute to our understanding of pathogenesis.",

author = "Chaitanya Kurhade and Sarah Schreier and Lee, \{Yi Ping\} and Loreen Zegenhagen and Marika Hjertqvist and Gerhard Dobler and Andrea Kr{\"o}ger and {\"O}verby, \{Anna K.\}",

year = "2018",

month = sep,

doi = "10.3201/eid2409.171825",

language = "English (US)",

volume = "24",

pages = "1709--1712",

journal = "Emerging infectious diseases",

issn = "1080-6040",

publisher = "Centers for Disease Control and Prevention (CDC)",

number = "9",

}

TY - JOUR

T1 - Correlation of severity of human tick-borne encephalitis virus disease and pathogenicity in mice

AU - Kurhade, Chaitanya

AU - Schreier, Sarah

AU - Lee, Yi Ping

AU - Zegenhagen, Loreen

AU - Hjertqvist, Marika

AU - Dobler, Gerhard

AU - Kröger, Andrea

AU - Överby, Anna K.

PY - 2018/9

Y1 - 2018/9

N2 - We compared 2 tick-borne encephalitis virus strains isolated from 2 different foci that cause different symptoms in tick-borne encephalitis patients, from neurologic to mild gastrointestinal symptoms. We compared neuroinvasiveness, neurovirulence, and proinflammatory cytokine response in mice and found unique differences that contribute to our understanding of pathogenesis.

AB - We compared 2 tick-borne encephalitis virus strains isolated from 2 different foci that cause different symptoms in tick-borne encephalitis patients, from neurologic to mild gastrointestinal symptoms. We compared neuroinvasiveness, neurovirulence, and proinflammatory cytokine response in mice and found unique differences that contribute to our understanding of pathogenesis.

UR - https://www.scopus.com/pages/publications/85052211848

UR - https://www.scopus.com/inward/citedby.url?scp=85052211848&partnerID=8YFLogxK

U2 - 10.3201/eid2409.171825

DO - 10.3201/eid2409.171825

M3 - Article

C2 - 30124404

AN - SCOPUS:85052211848

SN - 1080-6040

VL - 24

SP - 1709

EP - 1712

JO - Emerging infectious diseases

JF - Emerging infectious diseases

IS - 9

ER -

Correlation of severity of human tick-borne encephalitis virus disease and pathogenicity in mice

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this