Craniofacial resections in the elderly

An outcome study

Stephen J. Hentschel, Remi Nader, Dima Suki, Amer Dastgir, David Callender, Franco DeMonte

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Object. The elderly population is increasing in number and is healthier now than in the past. The purpose of this study was to examine complications and outcomes following craniofacial resection (CFR) in elderly patients and to compare findings with those of a matched younger cohort. Methods. All patients 70 years of age or older undergoing CFR at the M. D. Anderson Cancer Center (elderly group) between December 1992 and July 2003 were identified by examining the Department of Neurosurgery database. A random cohort of 28 patients younger than 70 years of age (control group) was selected from the overall population of patients who underwent CFR. There were 28 patients ranging in age from 70 to 84 years (median 74 years). Major local complications occurred in seven elderly patients (25%) and in six control patients (21%) (p = 0.75), and major systemic complications occurred in nine elderly patients (32%) and in three control patients (11%) (p = 0.05). There was one perioperative death in both groups of patients. The median duration of disease-specific survival for the elderly patients was not reached (mean 6.8 years); however, it was 8.3 years for control patients (p = 0.24). Predictors of poorer overall survival from a multivariate analysis of the elderly group included presence of cardiac disease (p = 0.005), a major systemic perioperative complication (p = 0.03), and a preoperative Karnofsky Performance Scale score less than 100 (p = 0.04). Conclusions. In this study of elderly patients who underwent CFR, there was no difference in disease-specific survival when compared with a matched cohort of younger patients. There was, however, an increased incidence of perioperative major systemic complications in the elderly group.

Original languageEnglish (US)
Pages (from-to)935-943
Number of pages9
JournalJournal of Neurosurgery
Volume101
Issue number6
DOIs
StatePublished - Dec 2004
Externally publishedYes

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Outcome Assessment (Health Care)
Survival
Karnofsky Performance Status
Neurosurgery
Population
Heart Diseases
Multivariate Analysis
Age Groups
Databases
Control Groups
Incidence

Keywords

  • Anterolateral skull base neoplasm
  • Craniofacial resection
  • Elderly
  • Outcome

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Cite this

Hentschel, S. J., Nader, R., Suki, D., Dastgir, A., Callender, D., & DeMonte, F. (2004). Craniofacial resections in the elderly: An outcome study. Journal of Neurosurgery, 101(6), 935-943. https://doi.org/10.3171/jns.2004.101.6.0935

Craniofacial resections in the elderly : An outcome study. / Hentschel, Stephen J.; Nader, Remi; Suki, Dima; Dastgir, Amer; Callender, David; DeMonte, Franco.

In: Journal of Neurosurgery, Vol. 101, No. 6, 12.2004, p. 935-943.

Research output: Contribution to journalArticle

Hentschel, SJ, Nader, R, Suki, D, Dastgir, A, Callender, D & DeMonte, F 2004, 'Craniofacial resections in the elderly: An outcome study', Journal of Neurosurgery, vol. 101, no. 6, pp. 935-943. https://doi.org/10.3171/jns.2004.101.6.0935
Hentschel SJ, Nader R, Suki D, Dastgir A, Callender D, DeMonte F. Craniofacial resections in the elderly: An outcome study. Journal of Neurosurgery. 2004 Dec;101(6):935-943. https://doi.org/10.3171/jns.2004.101.6.0935
Hentschel, Stephen J. ; Nader, Remi ; Suki, Dima ; Dastgir, Amer ; Callender, David ; DeMonte, Franco. / Craniofacial resections in the elderly : An outcome study. In: Journal of Neurosurgery. 2004 ; Vol. 101, No. 6. pp. 935-943.
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abstract = "Object. The elderly population is increasing in number and is healthier now than in the past. The purpose of this study was to examine complications and outcomes following craniofacial resection (CFR) in elderly patients and to compare findings with those of a matched younger cohort. Methods. All patients 70 years of age or older undergoing CFR at the M. D. Anderson Cancer Center (elderly group) between December 1992 and July 2003 were identified by examining the Department of Neurosurgery database. A random cohort of 28 patients younger than 70 years of age (control group) was selected from the overall population of patients who underwent CFR. There were 28 patients ranging in age from 70 to 84 years (median 74 years). Major local complications occurred in seven elderly patients (25{\%}) and in six control patients (21{\%}) (p = 0.75), and major systemic complications occurred in nine elderly patients (32{\%}) and in three control patients (11{\%}) (p = 0.05). There was one perioperative death in both groups of patients. The median duration of disease-specific survival for the elderly patients was not reached (mean 6.8 years); however, it was 8.3 years for control patients (p = 0.24). Predictors of poorer overall survival from a multivariate analysis of the elderly group included presence of cardiac disease (p = 0.005), a major systemic perioperative complication (p = 0.03), and a preoperative Karnofsky Performance Scale score less than 100 (p = 0.04). Conclusions. In this study of elderly patients who underwent CFR, there was no difference in disease-specific survival when compared with a matched cohort of younger patients. There was, however, an increased incidence of perioperative major systemic complications in the elderly group.",
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