Creating the invisible man

A. J. Welch; Chris Humphrey; Gracie Vargas; Oliver Stumpp; Chris Rylander

doi:10.1117/12.537256

Creating the invisible man

A. J. Welch, Chris Humphrey, Gracie Vargas, Oliver Stumpp, Chris Rylander

Research output: Contribution to journal › Conference article › peer-review

Abstract

Our recent research has shown that skin becomes temporarily transparent when a hyper-osmotic agent such as glycerol is introduced into the tissue. Local dehydration and index matching reduce light scattering which increases the penetration depth of collimated light. We have shown that when glycerol is applied to in vivo hamster skin, the resulting transparency is sufficient to allow visualization of blood vessels, and there is a temporary reduction in local blood flow. The reduced blood flow combined with greater light delivery significantly reduces the laser fluence rate [W/cm ²] required to coagulate dermal blood vessels.

Original language	English (US)
Pages (from-to)	285-290
Number of pages	6
Journal	Proceedings of SPIE - The International Society for Optical Engineering
Volume	5319
DOIs	https://doi.org/10.1117/12.537256
State	Published - 2004
Event	Progress in Biomedical Optics and Imaging - Laser Interaction with Tissue and Cells XV - San Jose, CA, United States Duration: Jan 26 2004 → Jan 28 2004

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Condensed Matter Physics
Computer Science Applications
Applied Mathematics
Electrical and Electronic Engineering

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10.1117/12.537256

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title = "Creating the invisible man",

abstract = "Our recent research has shown that skin becomes temporarily transparent when a hyper-osmotic agent such as glycerol is introduced into the tissue. Local dehydration and index matching reduce light scattering which increases the penetration depth of collimated light. We have shown that when glycerol is applied to in vivo hamster skin, the resulting transparency is sufficient to allow visualization of blood vessels, and there is a temporary reduction in local blood flow. The reduced blood flow combined with greater light delivery significantly reduces the laser fluence rate [W/cm 2] required to coagulate dermal blood vessels.",

author = "Welch, {A. J.} and Chris Humphrey and Gracie Vargas and Oliver Stumpp and Chris Rylander",

year = "2004",

doi = "10.1117/12.537256",

language = "English (US)",

volume = "5319",

pages = "285--290",

journal = "Proceedings of SPIE - The International Society for Optical Engineering",

issn = "0277-786X",

publisher = "SPIE",

note = "Progress in Biomedical Optics and Imaging - Laser Interaction with Tissue and Cells XV ; Conference date: 26-01-2004 Through 28-01-2004",

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T1 - Creating the invisible man

AU - Welch, A. J.

AU - Humphrey, Chris

AU - Vargas, Gracie

AU - Stumpp, Oliver

AU - Rylander, Chris

PY - 2004

Y1 - 2004

N2 - Our recent research has shown that skin becomes temporarily transparent when a hyper-osmotic agent such as glycerol is introduced into the tissue. Local dehydration and index matching reduce light scattering which increases the penetration depth of collimated light. We have shown that when glycerol is applied to in vivo hamster skin, the resulting transparency is sufficient to allow visualization of blood vessels, and there is a temporary reduction in local blood flow. The reduced blood flow combined with greater light delivery significantly reduces the laser fluence rate [W/cm 2] required to coagulate dermal blood vessels.

AB - Our recent research has shown that skin becomes temporarily transparent when a hyper-osmotic agent such as glycerol is introduced into the tissue. Local dehydration and index matching reduce light scattering which increases the penetration depth of collimated light. We have shown that when glycerol is applied to in vivo hamster skin, the resulting transparency is sufficient to allow visualization of blood vessels, and there is a temporary reduction in local blood flow. The reduced blood flow combined with greater light delivery significantly reduces the laser fluence rate [W/cm 2] required to coagulate dermal blood vessels.

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DO - 10.1117/12.537256

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AN - SCOPUS:5644290811

SN - 0277-786X

VL - 5319

SP - 285

EP - 290

JO - Proceedings of SPIE - The International Society for Optical Engineering

JF - Proceedings of SPIE - The International Society for Optical Engineering

T2 - Progress in Biomedical Optics and Imaging - Laser Interaction with Tissue and Cells XV

Y2 - 26 January 2004 through 28 January 2004

ER -

Creating the invisible man

Abstract

ASJC Scopus subject areas

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