Creating the invisible man

A. J. Welch, Chris Humphrey, Gracie Vargas, Oliver Stumpp, Chris Rylander

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Our recent research has shown that skin becomes temporarily transparent when a hyper-osmotic agent such as glycerol is introduced into the tissue. Local dehydration and index matching reduce light scattering which increases the penetration depth of collimated light. We have shown that when glycerol is applied to in vivo hamster skin, the resulting transparency is sufficient to allow visualization of blood vessels, and there is a temporary reduction in local blood flow. The reduced blood flow combined with greater light delivery significantly reduces the laser fluence rate [W/cm 2] required to coagulate dermal blood vessels.

Original languageEnglish (US)
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
EditorsS.L. Jacques, W.P. Roach
Pages285-290
Number of pages6
Volume5319
DOIs
StatePublished - 2004
EventProgress in Biomedical Optics and Imaging - Laser Interaction with Tissue and Cells XV - San Jose, CA, United States
Duration: Jan 26 2004Jan 28 2004

Other

OtherProgress in Biomedical Optics and Imaging - Laser Interaction with Tissue and Cells XV
CountryUnited States
CitySan Jose, CA
Period1/26/041/28/04

Fingerprint

blood vessels
Blood vessels
blood flow
glycerols
Glycerol
Skin
Blood
hamsters
Dehydration
dehydration
Light scattering
Transparency
delivery
fluence
light scattering
penetration
Visualization
Tissue
Lasers
lasers

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Condensed Matter Physics

Cite this

Welch, A. J., Humphrey, C., Vargas, G., Stumpp, O., & Rylander, C. (2004). Creating the invisible man. In S. L. Jacques, & W. P. Roach (Eds.), Proceedings of SPIE - The International Society for Optical Engineering (Vol. 5319, pp. 285-290) https://doi.org/10.1117/12.537256

Creating the invisible man. / Welch, A. J.; Humphrey, Chris; Vargas, Gracie; Stumpp, Oliver; Rylander, Chris.

Proceedings of SPIE - The International Society for Optical Engineering. ed. / S.L. Jacques; W.P. Roach. Vol. 5319 2004. p. 285-290.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Welch, AJ, Humphrey, C, Vargas, G, Stumpp, O & Rylander, C 2004, Creating the invisible man. in SL Jacques & WP Roach (eds), Proceedings of SPIE - The International Society for Optical Engineering. vol. 5319, pp. 285-290, Progress in Biomedical Optics and Imaging - Laser Interaction with Tissue and Cells XV, San Jose, CA, United States, 1/26/04. https://doi.org/10.1117/12.537256
Welch AJ, Humphrey C, Vargas G, Stumpp O, Rylander C. Creating the invisible man. In Jacques SL, Roach WP, editors, Proceedings of SPIE - The International Society for Optical Engineering. Vol. 5319. 2004. p. 285-290 https://doi.org/10.1117/12.537256
Welch, A. J. ; Humphrey, Chris ; Vargas, Gracie ; Stumpp, Oliver ; Rylander, Chris. / Creating the invisible man. Proceedings of SPIE - The International Society for Optical Engineering. editor / S.L. Jacques ; W.P. Roach. Vol. 5319 2004. pp. 285-290
@inproceedings{a028ec3c54094e10b8d08ab8fc91b386,
title = "Creating the invisible man",
abstract = "Our recent research has shown that skin becomes temporarily transparent when a hyper-osmotic agent such as glycerol is introduced into the tissue. Local dehydration and index matching reduce light scattering which increases the penetration depth of collimated light. We have shown that when glycerol is applied to in vivo hamster skin, the resulting transparency is sufficient to allow visualization of blood vessels, and there is a temporary reduction in local blood flow. The reduced blood flow combined with greater light delivery significantly reduces the laser fluence rate [W/cm 2] required to coagulate dermal blood vessels.",
author = "Welch, {A. J.} and Chris Humphrey and Gracie Vargas and Oliver Stumpp and Chris Rylander",
year = "2004",
doi = "10.1117/12.537256",
language = "English (US)",
volume = "5319",
pages = "285--290",
editor = "S.L. Jacques and W.P. Roach",
booktitle = "Proceedings of SPIE - The International Society for Optical Engineering",

}

TY - GEN

T1 - Creating the invisible man

AU - Welch, A. J.

AU - Humphrey, Chris

AU - Vargas, Gracie

AU - Stumpp, Oliver

AU - Rylander, Chris

PY - 2004

Y1 - 2004

N2 - Our recent research has shown that skin becomes temporarily transparent when a hyper-osmotic agent such as glycerol is introduced into the tissue. Local dehydration and index matching reduce light scattering which increases the penetration depth of collimated light. We have shown that when glycerol is applied to in vivo hamster skin, the resulting transparency is sufficient to allow visualization of blood vessels, and there is a temporary reduction in local blood flow. The reduced blood flow combined with greater light delivery significantly reduces the laser fluence rate [W/cm 2] required to coagulate dermal blood vessels.

AB - Our recent research has shown that skin becomes temporarily transparent when a hyper-osmotic agent such as glycerol is introduced into the tissue. Local dehydration and index matching reduce light scattering which increases the penetration depth of collimated light. We have shown that when glycerol is applied to in vivo hamster skin, the resulting transparency is sufficient to allow visualization of blood vessels, and there is a temporary reduction in local blood flow. The reduced blood flow combined with greater light delivery significantly reduces the laser fluence rate [W/cm 2] required to coagulate dermal blood vessels.

UR - http://www.scopus.com/inward/record.url?scp=5644290811&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=5644290811&partnerID=8YFLogxK

U2 - 10.1117/12.537256

DO - 10.1117/12.537256

M3 - Conference contribution

AN - SCOPUS:5644290811

VL - 5319

SP - 285

EP - 290

BT - Proceedings of SPIE - The International Society for Optical Engineering

A2 - Jacques, S.L.

A2 - Roach, W.P.

ER -