Crimean-Congo haemorrhagic fever: A seroepidemiological and tick survey in the Sultanate of Oman

R. J. Williams, S. Al-Busaidy, F. R. Mehta, G. O. Maupin, K. D. Wagoner, S. Al-Awaidy, A. J M Suleiman, A. S. Khan, C. J. Peters, Thomas Ksiazek

Research output: Contribution to journalArticle

72 Citations (Scopus)

Abstract

In 1995 and 1996, 4 persons from the Sultanate of Oman were confirmed with clinical Crimean-Congo haemorrhagic fever (CCHF). To assess the prevalence of CCHF virus infection in Oman, a convenience sample of imported and domestic animals from farms, abattoirs and livestock markets was examined by enzyme-linked immunosorbent assay (ELISA) for immunoglobulin G (IgG) antibodies to CCHF virus. Ticks were collected from selected animals, identified, pooled by species, host and location and tested for evidence of infection with CCHF virus by antigen-capture ELISA. Serum samples from individuals working in animal and nonanimal contact-related jobs were also tested for CCHF antibodies. Serological evidence of infection was noted in 108 (22%) of 489 animals. Most of the ticks collected (618 of 912) from all species of sampled livestock were Hyalomma anatolicum anatolicum, a competent vector and reservoir of CCHF virus. 243 tick pools were tested for CCHF antigen, and 19 pools were positive. Of the individuals working in animal contact-related jobs, 73 (30.3%) of 241 non-Omani citizens and only 1 (2.4%) of 41 Omani Citizens were CCHF antibody-positive. Butchers were more likely to have CCHF antibody than persons in other job categories. The presence of clinical disease and the serological results for animals and humans and infected Hyalomma ticks provide ample evidence of the presence of CCHF virus in yet another country in the Arabian Peninsula.

Original languageEnglish (US)
Pages (from-to)99-106
Number of pages8
JournalTropical Medicine and International Health
Volume5
Issue number2
DOIs
StatePublished - 2000
Externally publishedYes

Fingerprint

Crimean-Congo hemorrhagic fever virus
Crimean Hemorrhagic Fever
Oman
Congo
Ticks
Antibodies
Livestock
Enzyme-Linked Immunosorbent Assay
Antigens
Abattoirs
Domestic Animals
Virus Diseases
Infection
Immunoglobulin G
Surveys and Questionnaires
Serum

Keywords

  • Crimean-Congo haemorrhagic fever
  • Hyalomma anatolicum
  • Oman

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Infectious Diseases
  • Parasitology
  • Immunology

Cite this

Crimean-Congo haemorrhagic fever : A seroepidemiological and tick survey in the Sultanate of Oman. / Williams, R. J.; Al-Busaidy, S.; Mehta, F. R.; Maupin, G. O.; Wagoner, K. D.; Al-Awaidy, S.; Suleiman, A. J M; Khan, A. S.; Peters, C. J.; Ksiazek, Thomas.

In: Tropical Medicine and International Health, Vol. 5, No. 2, 2000, p. 99-106.

Research output: Contribution to journalArticle

Williams, RJ, Al-Busaidy, S, Mehta, FR, Maupin, GO, Wagoner, KD, Al-Awaidy, S, Suleiman, AJM, Khan, AS, Peters, CJ & Ksiazek, T 2000, 'Crimean-Congo haemorrhagic fever: A seroepidemiological and tick survey in the Sultanate of Oman', Tropical Medicine and International Health, vol. 5, no. 2, pp. 99-106. https://doi.org/10.1046/j.1365-3156.2000.00524.x
Williams, R. J. ; Al-Busaidy, S. ; Mehta, F. R. ; Maupin, G. O. ; Wagoner, K. D. ; Al-Awaidy, S. ; Suleiman, A. J M ; Khan, A. S. ; Peters, C. J. ; Ksiazek, Thomas. / Crimean-Congo haemorrhagic fever : A seroepidemiological and tick survey in the Sultanate of Oman. In: Tropical Medicine and International Health. 2000 ; Vol. 5, No. 2. pp. 99-106.
@article{e2b04285911c43ff9c6c1aa163e7ea15,
title = "Crimean-Congo haemorrhagic fever: A seroepidemiological and tick survey in the Sultanate of Oman",
abstract = "In 1995 and 1996, 4 persons from the Sultanate of Oman were confirmed with clinical Crimean-Congo haemorrhagic fever (CCHF). To assess the prevalence of CCHF virus infection in Oman, a convenience sample of imported and domestic animals from farms, abattoirs and livestock markets was examined by enzyme-linked immunosorbent assay (ELISA) for immunoglobulin G (IgG) antibodies to CCHF virus. Ticks were collected from selected animals, identified, pooled by species, host and location and tested for evidence of infection with CCHF virus by antigen-capture ELISA. Serum samples from individuals working in animal and nonanimal contact-related jobs were also tested for CCHF antibodies. Serological evidence of infection was noted in 108 (22{\%}) of 489 animals. Most of the ticks collected (618 of 912) from all species of sampled livestock were Hyalomma anatolicum anatolicum, a competent vector and reservoir of CCHF virus. 243 tick pools were tested for CCHF antigen, and 19 pools were positive. Of the individuals working in animal contact-related jobs, 73 (30.3{\%}) of 241 non-Omani citizens and only 1 (2.4{\%}) of 41 Omani Citizens were CCHF antibody-positive. Butchers were more likely to have CCHF antibody than persons in other job categories. The presence of clinical disease and the serological results for animals and humans and infected Hyalomma ticks provide ample evidence of the presence of CCHF virus in yet another country in the Arabian Peninsula.",
keywords = "Crimean-Congo haemorrhagic fever, Hyalomma anatolicum, Oman",
author = "Williams, {R. J.} and S. Al-Busaidy and Mehta, {F. R.} and Maupin, {G. O.} and Wagoner, {K. D.} and S. Al-Awaidy and Suleiman, {A. J M} and Khan, {A. S.} and Peters, {C. J.} and Thomas Ksiazek",
year = "2000",
doi = "10.1046/j.1365-3156.2000.00524.x",
language = "English (US)",
volume = "5",
pages = "99--106",
journal = "Tropical Medicine and International Health",
issn = "1360-2276",
publisher = "Wiley-Blackwell",
number = "2",

}

TY - JOUR

T1 - Crimean-Congo haemorrhagic fever

T2 - A seroepidemiological and tick survey in the Sultanate of Oman

AU - Williams, R. J.

AU - Al-Busaidy, S.

AU - Mehta, F. R.

AU - Maupin, G. O.

AU - Wagoner, K. D.

AU - Al-Awaidy, S.

AU - Suleiman, A. J M

AU - Khan, A. S.

AU - Peters, C. J.

AU - Ksiazek, Thomas

PY - 2000

Y1 - 2000

N2 - In 1995 and 1996, 4 persons from the Sultanate of Oman were confirmed with clinical Crimean-Congo haemorrhagic fever (CCHF). To assess the prevalence of CCHF virus infection in Oman, a convenience sample of imported and domestic animals from farms, abattoirs and livestock markets was examined by enzyme-linked immunosorbent assay (ELISA) for immunoglobulin G (IgG) antibodies to CCHF virus. Ticks were collected from selected animals, identified, pooled by species, host and location and tested for evidence of infection with CCHF virus by antigen-capture ELISA. Serum samples from individuals working in animal and nonanimal contact-related jobs were also tested for CCHF antibodies. Serological evidence of infection was noted in 108 (22%) of 489 animals. Most of the ticks collected (618 of 912) from all species of sampled livestock were Hyalomma anatolicum anatolicum, a competent vector and reservoir of CCHF virus. 243 tick pools were tested for CCHF antigen, and 19 pools were positive. Of the individuals working in animal contact-related jobs, 73 (30.3%) of 241 non-Omani citizens and only 1 (2.4%) of 41 Omani Citizens were CCHF antibody-positive. Butchers were more likely to have CCHF antibody than persons in other job categories. The presence of clinical disease and the serological results for animals and humans and infected Hyalomma ticks provide ample evidence of the presence of CCHF virus in yet another country in the Arabian Peninsula.

AB - In 1995 and 1996, 4 persons from the Sultanate of Oman were confirmed with clinical Crimean-Congo haemorrhagic fever (CCHF). To assess the prevalence of CCHF virus infection in Oman, a convenience sample of imported and domestic animals from farms, abattoirs and livestock markets was examined by enzyme-linked immunosorbent assay (ELISA) for immunoglobulin G (IgG) antibodies to CCHF virus. Ticks were collected from selected animals, identified, pooled by species, host and location and tested for evidence of infection with CCHF virus by antigen-capture ELISA. Serum samples from individuals working in animal and nonanimal contact-related jobs were also tested for CCHF antibodies. Serological evidence of infection was noted in 108 (22%) of 489 animals. Most of the ticks collected (618 of 912) from all species of sampled livestock were Hyalomma anatolicum anatolicum, a competent vector and reservoir of CCHF virus. 243 tick pools were tested for CCHF antigen, and 19 pools were positive. Of the individuals working in animal contact-related jobs, 73 (30.3%) of 241 non-Omani citizens and only 1 (2.4%) of 41 Omani Citizens were CCHF antibody-positive. Butchers were more likely to have CCHF antibody than persons in other job categories. The presence of clinical disease and the serological results for animals and humans and infected Hyalomma ticks provide ample evidence of the presence of CCHF virus in yet another country in the Arabian Peninsula.

KW - Crimean-Congo haemorrhagic fever

KW - Hyalomma anatolicum

KW - Oman

UR - http://www.scopus.com/inward/record.url?scp=0034016899&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0034016899&partnerID=8YFLogxK

U2 - 10.1046/j.1365-3156.2000.00524.x

DO - 10.1046/j.1365-3156.2000.00524.x

M3 - Article

C2 - 10747269

AN - SCOPUS:0034016899

VL - 5

SP - 99

EP - 106

JO - Tropical Medicine and International Health

JF - Tropical Medicine and International Health

SN - 1360-2276

IS - 2

ER -