Critical evaluation of a nanolaser for high repetition rate (1 kHz) MALDI-TOFMS

John A. McLean, William K. Russell, Justin M. Hettick, Joseph W. Morgan, Kent J. Gillig, David H. Russell

Research output: Contribution to conferencePaper

1 Scopus citations

Abstract

A high repetition rate Nd:YAG nanolaser operated for high throughput atmospheric pressure (AP) MALDI-TOFMS was evaluated. The diode-pumped, passively Q-switched laser operated at a repetition rate of 1 kHz and provided pulse energies of approximately 21 μJ. The Nd:YAG laser was compared with a nitrogen laser. The mass spectra were acquired using a quadrupole-time-of-flight mass spectrometer. It was found that the total acquisition time using the Nd:YAG laser at 1 kHz was 1-s, while that using the nitrogen laser at 30 Hz was 20-s. The results show that at least 30-fold throughput advantage can be achieved by operating at 1 kHz repetition rate for the nanolaser compared with conventional nitrogen laser system.

Original languageEnglish (US)
Pages725-726
Number of pages2
StatePublished - Dec 1 2002
Externally publishedYes
EventProceedings - 50th ASMS Conference on Mass Spectrometry and Allied Topics - Orlando, FL, United States
Duration: Jun 2 2002Jun 6 2002

Other

OtherProceedings - 50th ASMS Conference on Mass Spectrometry and Allied Topics
CountryUnited States
CityOrlando, FL
Period6/2/026/6/02

ASJC Scopus subject areas

  • Spectroscopy

Fingerprint Dive into the research topics of 'Critical evaluation of a nanolaser for high repetition rate (1 kHz) MALDI-TOFMS'. Together they form a unique fingerprint.

  • Cite this

    McLean, J. A., Russell, W. K., Hettick, J. M., Morgan, J. W., Gillig, K. J., & Russell, D. H. (2002). Critical evaluation of a nanolaser for high repetition rate (1 kHz) MALDI-TOFMS. 725-726. Paper presented at Proceedings - 50th ASMS Conference on Mass Spectrometry and Allied Topics, Orlando, FL, United States.