Abstract
A high repetition rate Nd:YAG nanolaser operated for high throughput atmospheric pressure (AP) MALDI-TOFMS was evaluated. The diode-pumped, passively Q-switched laser operated at a repetition rate of 1 kHz and provided pulse energies of approximately 21 μJ. The Nd:YAG laser was compared with a nitrogen laser. The mass spectra were acquired using a quadrupole-time-of-flight mass spectrometer. It was found that the total acquisition time using the Nd:YAG laser at 1 kHz was 1-s, while that using the nitrogen laser at 30 Hz was 20-s. The results show that at least 30-fold throughput advantage can be achieved by operating at 1 kHz repetition rate for the nanolaser compared with conventional nitrogen laser system.
| Original language | English (US) |
|---|---|
| Pages | 725-726 |
| Number of pages | 2 |
| State | Published - 2002 |
| Externally published | Yes |
| Event | Proceedings - 50th ASMS Conference on Mass Spectrometry and Allied Topics - Orlando, FL, United States Duration: Jun 2 2002 → Jun 6 2002 |
Other
| Other | Proceedings - 50th ASMS Conference on Mass Spectrometry and Allied Topics |
|---|---|
| Country/Territory | United States |
| City | Orlando, FL |
| Period | 6/2/02 → 6/6/02 |
ASJC Scopus subject areas
- Spectroscopy