Critical evaluation of a nanolaser for high repetition rate (1 kHz) MALDI-TOFMS

John A. McLean, William Russell, Justin M. Hettick, Joseph W. Morgan, Kent J. Gillig, David H. Russell

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

A high repetition rate Nd:YAG nanolaser operated for high throughput atmospheric pressure (AP) MALDI-TOFMS was evaluated. The diode-pumped, passively Q-switched laser operated at a repetition rate of 1 kHz and provided pulse energies of approximately 21 μJ. The Nd:YAG laser was compared with a nitrogen laser. The mass spectra were acquired using a quadrupole-time-of-flight mass spectrometer. It was found that the total acquisition time using the Nd:YAG laser at 1 kHz was 1-s, while that using the nitrogen laser at 30 Hz was 20-s. The results show that at least 30-fold throughput advantage can be achieved by operating at 1 kHz repetition rate for the nanolaser compared with conventional nitrogen laser system.

Original languageEnglish (US)
Title of host publicationProceedings - 50th ASMS Conference on Mass Spectrometry and Allied Topics
Pages725-726
Number of pages2
StatePublished - 2002
Externally publishedYes
EventProceedings - 50th ASMS Conference on Mass Spectrometry and Allied Topics - Orlando, FL, United States
Duration: Jun 2 2002Jun 6 2002

Other

OtherProceedings - 50th ASMS Conference on Mass Spectrometry and Allied Topics
CountryUnited States
CityOrlando, FL
Period6/2/026/6/02

Fingerprint

Lasers
Nitrogen
Throughput
Q switched lasers
Mass spectrometers
Atmospheric pressure
Diodes

ASJC Scopus subject areas

  • Spectroscopy

Cite this

McLean, J. A., Russell, W., Hettick, J. M., Morgan, J. W., Gillig, K. J., & Russell, D. H. (2002). Critical evaluation of a nanolaser for high repetition rate (1 kHz) MALDI-TOFMS. In Proceedings - 50th ASMS Conference on Mass Spectrometry and Allied Topics (pp. 725-726)

Critical evaluation of a nanolaser for high repetition rate (1 kHz) MALDI-TOFMS. / McLean, John A.; Russell, William; Hettick, Justin M.; Morgan, Joseph W.; Gillig, Kent J.; Russell, David H.

Proceedings - 50th ASMS Conference on Mass Spectrometry and Allied Topics. 2002. p. 725-726.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

McLean, JA, Russell, W, Hettick, JM, Morgan, JW, Gillig, KJ & Russell, DH 2002, Critical evaluation of a nanolaser for high repetition rate (1 kHz) MALDI-TOFMS. in Proceedings - 50th ASMS Conference on Mass Spectrometry and Allied Topics. pp. 725-726, Proceedings - 50th ASMS Conference on Mass Spectrometry and Allied Topics, Orlando, FL, United States, 6/2/02.
McLean JA, Russell W, Hettick JM, Morgan JW, Gillig KJ, Russell DH. Critical evaluation of a nanolaser for high repetition rate (1 kHz) MALDI-TOFMS. In Proceedings - 50th ASMS Conference on Mass Spectrometry and Allied Topics. 2002. p. 725-726
McLean, John A. ; Russell, William ; Hettick, Justin M. ; Morgan, Joseph W. ; Gillig, Kent J. ; Russell, David H. / Critical evaluation of a nanolaser for high repetition rate (1 kHz) MALDI-TOFMS. Proceedings - 50th ASMS Conference on Mass Spectrometry and Allied Topics. 2002. pp. 725-726
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