Abstract
Case:A 38-year-old woman presented to our clinic with right knee pain and difficulty ambulating. After cultures were obtained, a cryptococcal infection of the patella was identified. Subsequent workup revealed previously undiagnosed HIV/AIDS and a disseminated cryptococcal infection.Conclusion:Over a 20-month course, the patient was treated with fluconazole and antiretroviral therapy with very limited medication compliance. The disseminated infection caused cutaneous, hepatic, and cerebral complications. Eventually, compliance improved, and a final procedure to obtain post-treatment cultures and apply antifungal bone matrix was completed. The patient cleared the infection and will likely require lifetime antifungal treatment.
Original language | English (US) |
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Article number | e24.00304 |
Journal | JBJS case connector |
Volume | 14 |
Issue number | 3 |
DOIs | |
State | Published - Aug 29 2024 |
Externally published | Yes |
Keywords
- Cryptococcus
- HIV
- immunodeficiency
- infection
- osteomyelitis
- patella
ASJC Scopus subject areas
- Surgery
- Orthopedics and Sports Medicine