Cryptococcal Osteomyelitis of the Patella: A Case Report

Jacob Harper, Paul J. Weatherby, Mark A. Foreman

Research output: Contribution to journalArticlepeer-review

Abstract

Case:A 38-year-old woman presented to our clinic with right knee pain and difficulty ambulating. After cultures were obtained, a cryptococcal infection of the patella was identified. Subsequent workup revealed previously undiagnosed HIV/AIDS and a disseminated cryptococcal infection.Conclusion:Over a 20-month course, the patient was treated with fluconazole and antiretroviral therapy with very limited medication compliance. The disseminated infection caused cutaneous, hepatic, and cerebral complications. Eventually, compliance improved, and a final procedure to obtain post-treatment cultures and apply antifungal bone matrix was completed. The patient cleared the infection and will likely require lifetime antifungal treatment.

Original languageEnglish (US)
Article numbere24.00304
JournalJBJS case connector
Volume14
Issue number3
DOIs
StatePublished - Aug 29 2024
Externally publishedYes

Keywords

  • Cryptococcus
  • HIV
  • immunodeficiency
  • infection
  • osteomyelitis
  • patella

ASJC Scopus subject areas

  • Surgery
  • Orthopedics and Sports Medicine

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