Cutaneous Histoplasmosis in a Renal Transplant Patient Presenting With Hand and Forearm Necrotizing Myofasciitis

Histoplasmosis rarely manifests as a primary infection of the extremities, but when it does, the damage inflicted can be severe. We present a case report of cutaneous histoplasmosis of the upper extremity due to direct inoculation in a renal transplant patient, presenting as myofasciitis. The patient initially had a salvaged upper extremity that was functional, but a persistent infection recurred with aggressive myofasciitis requiring a subsequent amputation.