Cutting-edge advances in the medical management of obstetrical hemorrhage

Luis D. Pacheco, George R. Saade, Alfredo F. Gei, Gary D.V. Hankins

Research output: Contribution to journalReview articlepeer-review

53 Scopus citations


Hemorrhagic shock is the most common form of shock encountered in obstetric practice. Interventions that may limit transfusion requirements include normovolemic hemodilution, use of recombinant activated factor VII, selective embolization of pelvic vessels by interventional radiology, and the use of the cell saver intraoperatively. Current understanding of the mechanisms of acute coagulopathy calls into question the current transfusion guidelines, leading to a tendency to apply massive transfusion protocols based on hemostatic resuscitation despite lack of prospective data.

Original languageEnglish (US)
Pages (from-to)526-532
Number of pages7
JournalAmerican journal of obstetrics and gynecology
Issue number6
StatePublished - Dec 2011


  • hemorrhage
  • hemostatic resuscitation
  • pregnancy

ASJC Scopus subject areas

  • Obstetrics and Gynecology


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