CYCLIC DEPOSITION OF CALCIUM SALTS DURING GROWTH OF CHOLESTEROL GALLSTONES.

Peter F. Malet, Norman E. Weston, Bruce W. Trotman, Roger D. Soloway

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Some cholesterol gallstones contain darkly pigmented centers or peripheral concentric pigmented bands. We examined the cross-sectional surface of three cholesterol gallstones which contained both central and peripheral pigmented areas with electronprobe microanalysis (EPM) and energy dispersive x-ray microanalysis (EDXA) to determine the elemental composition of the pigmented regions. Linear EPM across the cross-sectional surface of the stones demonstrated that most of the pigmented regions of all three stones had high Ca and P signals; the nonpigmented intervening areas had markedly lower or no detectable Ca and P signals. In two of the three stones, high O signals coincided with the high Ca and P signals suggesting that both calcium bilirubinate and calcium phosphate were present in these pigmented areas. EDXA of the central and peripheral pigmented areas of each stone confirmed the presence of a high Ca signal. Our results demonstrate that in some cholesterol gallstones there is cyclic deposition of calcium bilirubinate and other calcium salts.

Original languageEnglish
Pages (from-to)775-779
Number of pages5
JournalScanning Electron Microscopy
Issue numberpt 2
StatePublished - 1985
Externally publishedYes

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Cholesterol
Microanalysis
Gallstones
Calcium
Salts
Bilirubin
Growth
X-Rays
X rays
Calcium phosphate
Chemical analysis

ASJC Scopus subject areas

  • Biophysics
  • Control and Systems Engineering

Cite this

Malet, P. F., Weston, N. E., Trotman, B. W., & Soloway, R. D. (1985). CYCLIC DEPOSITION OF CALCIUM SALTS DURING GROWTH OF CHOLESTEROL GALLSTONES. Scanning Electron Microscopy, (pt 2), 775-779.

CYCLIC DEPOSITION OF CALCIUM SALTS DURING GROWTH OF CHOLESTEROL GALLSTONES. / Malet, Peter F.; Weston, Norman E.; Trotman, Bruce W.; Soloway, Roger D.

In: Scanning Electron Microscopy, No. pt 2, 1985, p. 775-779.

Research output: Contribution to journalArticle

Malet, PF, Weston, NE, Trotman, BW & Soloway, RD 1985, 'CYCLIC DEPOSITION OF CALCIUM SALTS DURING GROWTH OF CHOLESTEROL GALLSTONES.', Scanning Electron Microscopy, no. pt 2, pp. 775-779.
Malet, Peter F. ; Weston, Norman E. ; Trotman, Bruce W. ; Soloway, Roger D. / CYCLIC DEPOSITION OF CALCIUM SALTS DURING GROWTH OF CHOLESTEROL GALLSTONES. In: Scanning Electron Microscopy. 1985 ; No. pt 2. pp. 775-779.
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