Cyclophosphamide, adriamycin, methotrexate, and procarbazine (CAMP) effective four drug combination chemotherapy for metastatic non oat cell bronchogenic carcinoma

J. D. Bitran, R. K. Desser, T. R. DeMeester, M. Colman, R. Evans, A. Billings, M. Griem, L. Rubenstein, C. Shapiro, H. M. Golomb

Research output: Contribution to journalArticle

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Abstract

23 patients with metastatic non oat cell bronchogenic carcinoma (MNOBC) were treated with cyclophosphamide, adriamycin, methotrexate, and procarbazine (CAMP) after radiation therapy. Objective responses were seen in 11 of 23 patients (48%) with a projected median survival time of 12.5 mth for responding patients and patients with stable disease. Lung, liver and cutaneous sites of involvement proved to be highly responsive; bone involvement was less responsive. CAMP is an effective combination in the treatment of MNOBC and its use in patients with less advanced disease should be explored.

Original languageEnglish (US)
Pages (from-to)1225-1230
Number of pages6
JournalCancer Treatment Reports
Volume60
Issue number9
StatePublished - 1976
Externally publishedYes

Fingerprint

Procarbazine
Small Cell Carcinoma
Bronchogenic Carcinoma
Drug Combinations
Combination Drug Therapy
Methotrexate
Doxorubicin
Cyclophosphamide
Radiotherapy
Bone and Bones
Lung
Skin
Survival
Liver

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

Bitran, J. D., Desser, R. K., DeMeester, T. R., Colman, M., Evans, R., Billings, A., ... Golomb, H. M. (1976). Cyclophosphamide, adriamycin, methotrexate, and procarbazine (CAMP) effective four drug combination chemotherapy for metastatic non oat cell bronchogenic carcinoma. Cancer Treatment Reports, 60(9), 1225-1230.

Cyclophosphamide, adriamycin, methotrexate, and procarbazine (CAMP) effective four drug combination chemotherapy for metastatic non oat cell bronchogenic carcinoma. / Bitran, J. D.; Desser, R. K.; DeMeester, T. R.; Colman, M.; Evans, R.; Billings, A.; Griem, M.; Rubenstein, L.; Shapiro, C.; Golomb, H. M.

In: Cancer Treatment Reports, Vol. 60, No. 9, 1976, p. 1225-1230.

Research output: Contribution to journalArticle

Bitran, JD, Desser, RK, DeMeester, TR, Colman, M, Evans, R, Billings, A, Griem, M, Rubenstein, L, Shapiro, C & Golomb, HM 1976, 'Cyclophosphamide, adriamycin, methotrexate, and procarbazine (CAMP) effective four drug combination chemotherapy for metastatic non oat cell bronchogenic carcinoma', Cancer Treatment Reports, vol. 60, no. 9, pp. 1225-1230.
Bitran, J. D. ; Desser, R. K. ; DeMeester, T. R. ; Colman, M. ; Evans, R. ; Billings, A. ; Griem, M. ; Rubenstein, L. ; Shapiro, C. ; Golomb, H. M. / Cyclophosphamide, adriamycin, methotrexate, and procarbazine (CAMP) effective four drug combination chemotherapy for metastatic non oat cell bronchogenic carcinoma. In: Cancer Treatment Reports. 1976 ; Vol. 60, No. 9. pp. 1225-1230.
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abstract = "23 patients with metastatic non oat cell bronchogenic carcinoma (MNOBC) were treated with cyclophosphamide, adriamycin, methotrexate, and procarbazine (CAMP) after radiation therapy. Objective responses were seen in 11 of 23 patients (48{\%}) with a projected median survival time of 12.5 mth for responding patients and patients with stable disease. Lung, liver and cutaneous sites of involvement proved to be highly responsive; bone involvement was less responsive. CAMP is an effective combination in the treatment of MNOBC and its use in patients with less advanced disease should be explored.",
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AU - Bitran, J. D.

AU - Desser, R. K.

AU - DeMeester, T. R.

AU - Colman, M.

AU - Evans, R.

AU - Billings, A.

AU - Griem, M.

AU - Rubenstein, L.

AU - Shapiro, C.

AU - Golomb, H. M.

PY - 1976

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