Cysteine proteinase inhibitors in murine cysticercosis

Salman Baig, Raymond T. Damian, Jorge Morales-Montor, Rupal Thazhath, Amr Ghaleb, Meredith Welch, Jamil Talhouk, A. Clinton White

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

We explored the prophylactic efficacies of two novel protease inhibitors in murine cysticercosis. Our results demonstrated a 95% and 80% reduction in parasite burden for mice injected with Z-LLL-FMK and Z-LLY-FMK, respectively. Further studies are merited on the role of cysteine proteinase inhibitors in treatment of cysticercosis.

Original languageEnglish (US)
Pages (from-to)2886-2888
Number of pages3
JournalAntimicrobial Agents and Chemotherapy
Volume50
Issue number8
DOIs
StatePublished - Aug 2006
Externally publishedYes

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Cysteine Proteinase Inhibitors
Cysticercosis
Protease Inhibitors
Parasites
benzyloxycarbonyl-leucyl-glucyl-tyrosine fluoromethyl ketone
benzyloxycarbonylleucyl-leucyl-leucine aldehyde

ASJC Scopus subject areas

  • Pharmacology (medical)

Cite this

Baig, S., Damian, R. T., Morales-Montor, J., Thazhath, R., Ghaleb, A., Welch, M., ... White, A. C. (2006). Cysteine proteinase inhibitors in murine cysticercosis. Antimicrobial Agents and Chemotherapy, 50(8), 2886-2888. https://doi.org/10.1128/AAC.01060-05

Cysteine proteinase inhibitors in murine cysticercosis. / Baig, Salman; Damian, Raymond T.; Morales-Montor, Jorge; Thazhath, Rupal; Ghaleb, Amr; Welch, Meredith; Talhouk, Jamil; White, A. Clinton.

In: Antimicrobial Agents and Chemotherapy, Vol. 50, No. 8, 08.2006, p. 2886-2888.

Research output: Contribution to journalArticle

Baig, S, Damian, RT, Morales-Montor, J, Thazhath, R, Ghaleb, A, Welch, M, Talhouk, J & White, AC 2006, 'Cysteine proteinase inhibitors in murine cysticercosis', Antimicrobial Agents and Chemotherapy, vol. 50, no. 8, pp. 2886-2888. https://doi.org/10.1128/AAC.01060-05
Baig S, Damian RT, Morales-Montor J, Thazhath R, Ghaleb A, Welch M et al. Cysteine proteinase inhibitors in murine cysticercosis. Antimicrobial Agents and Chemotherapy. 2006 Aug;50(8):2886-2888. https://doi.org/10.1128/AAC.01060-05
Baig, Salman ; Damian, Raymond T. ; Morales-Montor, Jorge ; Thazhath, Rupal ; Ghaleb, Amr ; Welch, Meredith ; Talhouk, Jamil ; White, A. Clinton. / Cysteine proteinase inhibitors in murine cysticercosis. In: Antimicrobial Agents and Chemotherapy. 2006 ; Vol. 50, No. 8. pp. 2886-2888.
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