Cysteine proteinase inhibitors in murine cysticercosis

Salman Baig; Raymond T. Damian; Jorge Morales-Montor; Rupal Thazhath; Amr Ghaleb; Meredith Welch; Jamil Talhouk; A. Clinton White

doi:10.1128/AAC.01060-05

Cysteine proteinase inhibitors in murine cysticercosis

Salman Baig, Raymond T. Damian, Jorge Morales-Montor, Rupal Thazhath, Amr Ghaleb, Meredith Welch, Jamil Talhouk, A. Clinton White

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Abstract

We explored the prophylactic efficacies of two novel protease inhibitors in murine cysticercosis. Our results demonstrated a 95% and 80% reduction in parasite burden for mice injected with Z-LLL-FMK and Z-LLY-FMK, respectively. Further studies are merited on the role of cysteine proteinase inhibitors in treatment of cysticercosis.

Original language	English (US)
Pages (from-to)	2886-2888
Number of pages	3
Journal	Antimicrobial agents and chemotherapy
Volume	50
Issue number	8
DOIs	https://doi.org/10.1128/AAC.01060-05
State	Published - Aug 2006
Externally published	Yes

ASJC Scopus subject areas

Pharmacology
Pharmacology (medical)
Infectious Diseases

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title = "Cysteine proteinase inhibitors in murine cysticercosis",

abstract = "We explored the prophylactic efficacies of two novel protease inhibitors in murine cysticercosis. Our results demonstrated a 95% and 80% reduction in parasite burden for mice injected with Z-LLL-FMK and Z-LLY-FMK, respectively. Further studies are merited on the role of cysteine proteinase inhibitors in treatment of cysticercosis.",

author = "Salman Baig and Damian, {Raymond T.} and Jorge Morales-Montor and Rupal Thazhath and Amr Ghaleb and Meredith Welch and Jamil Talhouk and White, {A. Clinton}",

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AU - Damian, Raymond T.

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AU - Thazhath, Rupal

AU - Ghaleb, Amr

AU - Welch, Meredith

AU - Talhouk, Jamil

AU - White, A. Clinton

PY - 2006/8

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AB - We explored the prophylactic efficacies of two novel protease inhibitors in murine cysticercosis. Our results demonstrated a 95% and 80% reduction in parasite burden for mice injected with Z-LLL-FMK and Z-LLY-FMK, respectively. Further studies are merited on the role of cysteine proteinase inhibitors in treatment of cysticercosis.

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Cysteine proteinase inhibitors in murine cysticercosis

Abstract

ASJC Scopus subject areas

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