Cysteine proteinase inhibitors in murine cysticercosis

Salman Baig, Raymond T. Damian, Jorge Morales-Montor, Rupal Thazhath, Amr Ghaleb, Meredith Welch, Jamil Talhouk, A. Clinton White

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

We explored the prophylactic efficacies of two novel protease inhibitors in murine cysticercosis. Our results demonstrated a 95% and 80% reduction in parasite burden for mice injected with Z-LLL-FMK and Z-LLY-FMK, respectively. Further studies are merited on the role of cysteine proteinase inhibitors in treatment of cysticercosis.

Original languageEnglish (US)
Pages (from-to)2886-2888
Number of pages3
JournalAntimicrobial agents and chemotherapy
Volume50
Issue number8
DOIs
StatePublished - Aug 1 2006
Externally publishedYes

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ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases

Cite this

Baig, S., Damian, R. T., Morales-Montor, J., Thazhath, R., Ghaleb, A., Welch, M., Talhouk, J., & White, A. C. (2006). Cysteine proteinase inhibitors in murine cysticercosis. Antimicrobial agents and chemotherapy, 50(8), 2886-2888. https://doi.org/10.1128/AAC.01060-05