Cysteine proteinase inhibitors in murine cysticercosis

Salman Baig; Raymond T. Damian; Jorge Morales-Montor; Rupal Thazhath; Amr Ghaleb; Meredith Welch; Jamil Talhouk; A. Clinton White

doi:10.1128/AAC.01060-05

Cysteine proteinase inhibitors in murine cysticercosis

Salman Baig
, Raymond T. Damian
, Jorge Morales-Montor
, Rupal Thazhath
, Amr Ghaleb
, Meredith Welch
, Jamil Talhouk
, A. Clinton White

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

We explored the prophylactic efficacies of two novel protease inhibitors in murine cysticercosis. Our results demonstrated a 95% and 80% reduction in parasite burden for mice injected with Z-LLL-FMK and Z-LLY-FMK, respectively. Further studies are merited on the role of cysteine proteinase inhibitors in treatment of cysticercosis.

Original language	English (US)
Pages (from-to)	2886-2888
Number of pages	3
Journal	Antimicrobial agents and chemotherapy
Volume	50
Issue number	8
DOIs	https://doi.org/10.1128/AAC.01060-05
State	Published - Aug 2006
Externally published	Yes

ASJC Scopus subject areas

Pharmacology
Pharmacology (medical)
Infectious Diseases

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10.1128/AAC.01060-05

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title = "Cysteine proteinase inhibitors in murine cysticercosis",

abstract = "We explored the prophylactic efficacies of two novel protease inhibitors in murine cysticercosis. Our results demonstrated a 95\% and 80\% reduction in parasite burden for mice injected with Z-LLL-FMK and Z-LLY-FMK, respectively. Further studies are merited on the role of cysteine proteinase inhibitors in treatment of cysticercosis.",

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year = "2006",

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AU - Baig, Salman

AU - Damian, Raymond T.

AU - Morales-Montor, Jorge

AU - Thazhath, Rupal

AU - Ghaleb, Amr

AU - Welch, Meredith

AU - Talhouk, Jamil

AU - White, A. Clinton

PY - 2006/8

Y1 - 2006/8

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AB - We explored the prophylactic efficacies of two novel protease inhibitors in murine cysticercosis. Our results demonstrated a 95% and 80% reduction in parasite burden for mice injected with Z-LLL-FMK and Z-LLY-FMK, respectively. Further studies are merited on the role of cysteine proteinase inhibitors in treatment of cysticercosis.

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UR - https://www.scopus.com/pages/publications/33746916090#tab=citedBy

U2 - 10.1128/AAC.01060-05

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M3 - Article

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AN - SCOPUS:33746916090

SN - 0066-4804

VL - 50

SP - 2886

EP - 2888

JO - Antimicrobial agents and chemotherapy

JF - Antimicrobial agents and chemotherapy

IS - 8

ER -

Cysteine proteinase inhibitors in murine cysticercosis

Abstract

ASJC Scopus subject areas

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