Cystic fibrosis: Characterization of the inhibitor to ciliary action in oyster gills

Barbara H. Bowman, Michael L. McCombs, Lillian Lockhart

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The inhibitor to oyster ciliary activity was isolated from serum of cystic fibrosis patients and heterozygotes. The inhibiting protein fraction was a cation as judged by electrophoresis; it had a molecular weight of 125,000 to 200,000 as judged by gel filtration; and on diethylaminoethyl-cellulose chromatography it eluted with the immunoglobulin G fraction. The analogous fraction in normal individuals did not inhibit oyster ciliary activity.

Original languageEnglish (US)
Pages (from-to)871-873
Number of pages3
Issue number3919
StatePublished - 1970


ASJC Scopus subject areas

  • General

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