Cystic fibrosis in pregnancy

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Advances in the diagnosis and treatment of cystic fibrosis have resulted in increased survival for those afflicted with this disease. As a result, more women are reaching their reproductive years and will subsequently conceive. Multiple organ systems are affected during the course of cystic fibrosis and may impact on pregnancy; however, pulmonary complications play a major role in morbidity and mortality. Therefore, this article primarily focuses on the pulmonary aspects of cystic fibrosis as they relate to pregnancy. The current literature suggests a favorable outcome for the pregnancy when there is limited pulmonary dysfunction. Chronic severely impaired pulmonary function is associated with poorer pregnancy outcome; however, it is the acute deterioration of pulmonary function that may in fact be associated with the highest morbidity and mortality for both mother and infant. Aggressive management of pulmonary infection and function is essential, and pulmonary status should be evaluated on a monthly basis. The forced expiratory volume in 1 second (FEV1) and forced vital capacity (FVC) can be used to monitor pulmonary status. Close surveillance, aggressive management, and a team approach can and has resulted in successful pregnancy outcome in those women with cystic fibrosis.

Original languageEnglish (US)
Pages (from-to)307-312
Number of pages6
JournalSeminars in Perinatology
Volume21
Issue number4
DOIs
StatePublished - 1997

Fingerprint

Cystic Fibrosis
Pregnancy
Lung
Pregnancy Outcome
Morbidity
Mortality
Vital Capacity
Forced Expiratory Volume
Mothers
Survival
Infection

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Cystic fibrosis in pregnancy. / Olson, Gayle.

In: Seminars in Perinatology, Vol. 21, No. 4, 1997, p. 307-312.

Research output: Contribution to journalArticle

Olson, Gayle. / Cystic fibrosis in pregnancy. In: Seminars in Perinatology. 1997 ; Vol. 21, No. 4. pp. 307-312.
@article{f5cdfa1a9ac44172bd45734cdd3e20ed,
title = "Cystic fibrosis in pregnancy",
abstract = "Advances in the diagnosis and treatment of cystic fibrosis have resulted in increased survival for those afflicted with this disease. As a result, more women are reaching their reproductive years and will subsequently conceive. Multiple organ systems are affected during the course of cystic fibrosis and may impact on pregnancy; however, pulmonary complications play a major role in morbidity and mortality. Therefore, this article primarily focuses on the pulmonary aspects of cystic fibrosis as they relate to pregnancy. The current literature suggests a favorable outcome for the pregnancy when there is limited pulmonary dysfunction. Chronic severely impaired pulmonary function is associated with poorer pregnancy outcome; however, it is the acute deterioration of pulmonary function that may in fact be associated with the highest morbidity and mortality for both mother and infant. Aggressive management of pulmonary infection and function is essential, and pulmonary status should be evaluated on a monthly basis. The forced expiratory volume in 1 second (FEV1) and forced vital capacity (FVC) can be used to monitor pulmonary status. Close surveillance, aggressive management, and a team approach can and has resulted in successful pregnancy outcome in those women with cystic fibrosis.",
author = "Gayle Olson",
year = "1997",
doi = "10.1016/S0146-0005(97)80073-0",
language = "English (US)",
volume = "21",
pages = "307--312",
journal = "Seminars in Perinatology",
issn = "0146-0005",
publisher = "W.B. Saunders Ltd",
number = "4",

}

TY - JOUR

T1 - Cystic fibrosis in pregnancy

AU - Olson, Gayle

PY - 1997

Y1 - 1997

N2 - Advances in the diagnosis and treatment of cystic fibrosis have resulted in increased survival for those afflicted with this disease. As a result, more women are reaching their reproductive years and will subsequently conceive. Multiple organ systems are affected during the course of cystic fibrosis and may impact on pregnancy; however, pulmonary complications play a major role in morbidity and mortality. Therefore, this article primarily focuses on the pulmonary aspects of cystic fibrosis as they relate to pregnancy. The current literature suggests a favorable outcome for the pregnancy when there is limited pulmonary dysfunction. Chronic severely impaired pulmonary function is associated with poorer pregnancy outcome; however, it is the acute deterioration of pulmonary function that may in fact be associated with the highest morbidity and mortality for both mother and infant. Aggressive management of pulmonary infection and function is essential, and pulmonary status should be evaluated on a monthly basis. The forced expiratory volume in 1 second (FEV1) and forced vital capacity (FVC) can be used to monitor pulmonary status. Close surveillance, aggressive management, and a team approach can and has resulted in successful pregnancy outcome in those women with cystic fibrosis.

AB - Advances in the diagnosis and treatment of cystic fibrosis have resulted in increased survival for those afflicted with this disease. As a result, more women are reaching their reproductive years and will subsequently conceive. Multiple organ systems are affected during the course of cystic fibrosis and may impact on pregnancy; however, pulmonary complications play a major role in morbidity and mortality. Therefore, this article primarily focuses on the pulmonary aspects of cystic fibrosis as they relate to pregnancy. The current literature suggests a favorable outcome for the pregnancy when there is limited pulmonary dysfunction. Chronic severely impaired pulmonary function is associated with poorer pregnancy outcome; however, it is the acute deterioration of pulmonary function that may in fact be associated with the highest morbidity and mortality for both mother and infant. Aggressive management of pulmonary infection and function is essential, and pulmonary status should be evaluated on a monthly basis. The forced expiratory volume in 1 second (FEV1) and forced vital capacity (FVC) can be used to monitor pulmonary status. Close surveillance, aggressive management, and a team approach can and has resulted in successful pregnancy outcome in those women with cystic fibrosis.

UR - http://www.scopus.com/inward/record.url?scp=0030773029&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0030773029&partnerID=8YFLogxK

U2 - 10.1016/S0146-0005(97)80073-0

DO - 10.1016/S0146-0005(97)80073-0

M3 - Article

C2 - 9298719

AN - SCOPUS:0030773029

VL - 21

SP - 307

EP - 312

JO - Seminars in Perinatology

JF - Seminars in Perinatology

SN - 0146-0005

IS - 4

ER -