Cytodiagnosis in the autopsy suite

A tool for improving autopsy quality and resident education

Vicki J. Schnadig, Claudia P. Molina, Judith Aronson

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

• Context. - Despite several publications attesting to its accuracy and value, cytology is rarely used for preliminary autopsy diagnosis in the United States. Postmortem cytodiagnosis has the potential to increase the accuracy and specificity of the provisional and final autopsy diagnoses, increase resident interest in cytodiagnostic techniques, and direct pathologists to request pertinent special studies, such as microbial cultures and special stains. Objective. - To assess and illustrate the value of cytodiagnostic techniques for improving autopsy quality assurance and resident education. Design. - Eighty-five samples were evaluated from 49 nonconsecutive autopsies. Sixty-five focal lesions were sampled by direct scraping. Diffuse lung consolidation was sampled by fine-needle aspiration (20 samples). Smears and cytocentrifuge preparations of fine-needle aspirations were routinely stained by both Papanicolaou and Romanowski methods. Cytologic diagnoses were compared with final autopsy diagnoses, and both cytology and pertinent histology were reviewed. Results. - Clinical or radiographic antemortem site-specific diagnoses had been made in 28 (33%) of the 85 samples. A definite diagnosis was made by postmortem cytology in 68 (80%) of 85 samples, and these diagnoses could contribute to provisional autopsy diagnosis in 46 instances (68%). Resident and faculty enthusiasm for the use of cytology in the autopsy suite has increased during the 7 years following the study. Case examples illustrating the benefits of postmortem cytology are provided. Conclusions. - Postmortem cytology benefits both autopsy quality and resident education.

Original languageEnglish (US)
Pages (from-to)1056-1062
Number of pages7
JournalArchives of Pathology and Laboratory Medicine
Volume131
Issue number7
StatePublished - Jul 2007

Fingerprint

Cytodiagnosis
Autopsy
Cell Biology
Education
Fine Needle Biopsy
Publications
Histology
Coloring Agents
Lung

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Medical Laboratory Technology

Cite this

Cytodiagnosis in the autopsy suite : A tool for improving autopsy quality and resident education. / Schnadig, Vicki J.; Molina, Claudia P.; Aronson, Judith.

In: Archives of Pathology and Laboratory Medicine, Vol. 131, No. 7, 07.2007, p. 1056-1062.

Research output: Contribution to journalArticle

@article{d502ecca8b904841a3fc7d872551aa82,
title = "Cytodiagnosis in the autopsy suite: A tool for improving autopsy quality and resident education",
abstract = "• Context. - Despite several publications attesting to its accuracy and value, cytology is rarely used for preliminary autopsy diagnosis in the United States. Postmortem cytodiagnosis has the potential to increase the accuracy and specificity of the provisional and final autopsy diagnoses, increase resident interest in cytodiagnostic techniques, and direct pathologists to request pertinent special studies, such as microbial cultures and special stains. Objective. - To assess and illustrate the value of cytodiagnostic techniques for improving autopsy quality assurance and resident education. Design. - Eighty-five samples were evaluated from 49 nonconsecutive autopsies. Sixty-five focal lesions were sampled by direct scraping. Diffuse lung consolidation was sampled by fine-needle aspiration (20 samples). Smears and cytocentrifuge preparations of fine-needle aspirations were routinely stained by both Papanicolaou and Romanowski methods. Cytologic diagnoses were compared with final autopsy diagnoses, and both cytology and pertinent histology were reviewed. Results. - Clinical or radiographic antemortem site-specific diagnoses had been made in 28 (33{\%}) of the 85 samples. A definite diagnosis was made by postmortem cytology in 68 (80{\%}) of 85 samples, and these diagnoses could contribute to provisional autopsy diagnosis in 46 instances (68{\%}). Resident and faculty enthusiasm for the use of cytology in the autopsy suite has increased during the 7 years following the study. Case examples illustrating the benefits of postmortem cytology are provided. Conclusions. - Postmortem cytology benefits both autopsy quality and resident education.",
author = "Schnadig, {Vicki J.} and Molina, {Claudia P.} and Judith Aronson",
year = "2007",
month = "7",
language = "English (US)",
volume = "131",
pages = "1056--1062",
journal = "Archives of Pathology and Laboratory Medicine",
issn = "0003-9985",
publisher = "College of American Pathologists",
number = "7",

}

TY - JOUR

T1 - Cytodiagnosis in the autopsy suite

T2 - A tool for improving autopsy quality and resident education

AU - Schnadig, Vicki J.

AU - Molina, Claudia P.

AU - Aronson, Judith

PY - 2007/7

Y1 - 2007/7

N2 - • Context. - Despite several publications attesting to its accuracy and value, cytology is rarely used for preliminary autopsy diagnosis in the United States. Postmortem cytodiagnosis has the potential to increase the accuracy and specificity of the provisional and final autopsy diagnoses, increase resident interest in cytodiagnostic techniques, and direct pathologists to request pertinent special studies, such as microbial cultures and special stains. Objective. - To assess and illustrate the value of cytodiagnostic techniques for improving autopsy quality assurance and resident education. Design. - Eighty-five samples were evaluated from 49 nonconsecutive autopsies. Sixty-five focal lesions were sampled by direct scraping. Diffuse lung consolidation was sampled by fine-needle aspiration (20 samples). Smears and cytocentrifuge preparations of fine-needle aspirations were routinely stained by both Papanicolaou and Romanowski methods. Cytologic diagnoses were compared with final autopsy diagnoses, and both cytology and pertinent histology were reviewed. Results. - Clinical or radiographic antemortem site-specific diagnoses had been made in 28 (33%) of the 85 samples. A definite diagnosis was made by postmortem cytology in 68 (80%) of 85 samples, and these diagnoses could contribute to provisional autopsy diagnosis in 46 instances (68%). Resident and faculty enthusiasm for the use of cytology in the autopsy suite has increased during the 7 years following the study. Case examples illustrating the benefits of postmortem cytology are provided. Conclusions. - Postmortem cytology benefits both autopsy quality and resident education.

AB - • Context. - Despite several publications attesting to its accuracy and value, cytology is rarely used for preliminary autopsy diagnosis in the United States. Postmortem cytodiagnosis has the potential to increase the accuracy and specificity of the provisional and final autopsy diagnoses, increase resident interest in cytodiagnostic techniques, and direct pathologists to request pertinent special studies, such as microbial cultures and special stains. Objective. - To assess and illustrate the value of cytodiagnostic techniques for improving autopsy quality assurance and resident education. Design. - Eighty-five samples were evaluated from 49 nonconsecutive autopsies. Sixty-five focal lesions were sampled by direct scraping. Diffuse lung consolidation was sampled by fine-needle aspiration (20 samples). Smears and cytocentrifuge preparations of fine-needle aspirations were routinely stained by both Papanicolaou and Romanowski methods. Cytologic diagnoses were compared with final autopsy diagnoses, and both cytology and pertinent histology were reviewed. Results. - Clinical or radiographic antemortem site-specific diagnoses had been made in 28 (33%) of the 85 samples. A definite diagnosis was made by postmortem cytology in 68 (80%) of 85 samples, and these diagnoses could contribute to provisional autopsy diagnosis in 46 instances (68%). Resident and faculty enthusiasm for the use of cytology in the autopsy suite has increased during the 7 years following the study. Case examples illustrating the benefits of postmortem cytology are provided. Conclusions. - Postmortem cytology benefits both autopsy quality and resident education.

UR - http://www.scopus.com/inward/record.url?scp=34447309350&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=34447309350&partnerID=8YFLogxK

M3 - Article

VL - 131

SP - 1056

EP - 1062

JO - Archives of Pathology and Laboratory Medicine

JF - Archives of Pathology and Laboratory Medicine

SN - 0003-9985

IS - 7

ER -