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Cytoprotective effects of IAPs revealed by a small molecule antagonist
Stefanie Galbán
, Clara Hwang
, Julie M. Rumble
, Karolyn A. Oetjen
,
Casey W. Wright
, Alain Boudreault
, Jon Durkin
, John W. Gillard
, James B. Jaquith
, Stephen J. Morris
, Colin S. Duckett
Research output
:
Contribution to journal
›
Article
›
peer-review
39
Scopus citations
Overview
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Keyphrases
Inhibitor of Apoptosis Proteins
100%
X-linked
100%
Small Molecule Antagonist
100%
Synthetic Inhibitors
28%
CIAP1
28%
Apoptosis
14%
Relative Contribution
14%
Signaling Pathway
14%
Cell Signaling Pathways
14%
Tumor Cells
14%
Inhibitory Activity
14%
In Cancer
14%
Caspase
14%
Neoplastic Cells
14%
Nanomolar Concentrations
14%
Apoptotic Pathway
14%
Targeted Therapy
14%
Novel Class
14%
Cancer Therapy
14%
HCT116 Cells
14%
CIAP2
14%
Enhancement Effect
14%
Tumor Cell Lines
14%
Deregulated Expression
14%
X-linked Inhibitor of Apoptosis Protein
14%
Ubiquitin-mediated Degradation
14%
Line of Control
14%
Cytokine-induced Apoptosis Inhibitor 1
14%
Chemistry
Apoptotic
100%
Cytoprotective
100%
Signal Transduction
100%
Ubiquitins
100%
Biochemistry, Genetics and Molecular Biology
Small Molecule
100%
Inhibitor of Apoptosis
100%
Signal Transduction
11%
Ubiquitin
11%
Caspase
11%
Programmed Cell Death
11%
Targeted Therapy
11%
Pharmacology, Toxicology and Pharmaceutical Science
Cytoprotective Agent
100%
X Linked Inhibitor of Apoptosis
100%
Malignant Neoplasm
12%
Ubiquitin
12%
Caspase
12%
Cell Protein
12%
Neuroscience
Programmed Cell Death
100%
X Linked Inhibitor of Apoptosis
88%
Cell Line
11%
Caspase
11%
Cell Protein
11%
Ubiquitin
11%
Immunology and Microbiology
Programmed Cell Death
100%
Signal Transduction
10%
Tumor Cell
10%
Caspase
10%
Tumor Cell Line
10%
Ubiquitins
10%