DDX6 (Rck/p54) is required for efficient hepatitis C virus replication but not for internal ribosome entry site-directed translation

Keyphrases

• Hepatitis C Virus Replication 100%
• Site-directed 100%
• Internal Ribosome Entry Site 100%
• DDX6 100%
• Hepatitis C Virus 26%
• Knockdown 20%
• MiR-122 20%
• Small Interfering RNA (siRNA) 13%
• Helicase Activity 13%
• EYFP 13%
• Co-immunoprecipitation (co-IP) 6%
• Overexpression 6%
• Hepatitis C Virus RNA 6%
• MicroRNA 6%
• Cell Proliferation 6%
• Helicase 6%
• Cellular Homeostasis 6%
• Subgenomic 6%
• Virus Genome 6%
• Biogenesis 6%
• Hepatitis C Virus Core Protein 6%
• Hepatoma Cells 6%
• RNA-based 6%
• Translation Regulation 6%
• Virus Yield 6%
• Core Sequence 6%
• Whole Genome Amplification 6%
• Cellular RNA 6%
• Multiple Proteins 6%
• DEAD-box 6%
• Minimal Reduction 6%
• Pregenomic RNA (pgRNA) 6%
• Evolutionarily Conserved 6%
• Dominant-negative Effect 6%
• Cellular Translation 6%
• DEAD-box Helicase 6%

Immunology and Microbiology

• Viral Replication 100%
• Hepatitis C Virus 100%
• Internal Ribosome Entry Site 100%
• Ribonucleic Acid 63%
• Replication 18%
• Virus Genome 9%
• Cell Proliferation 9%
• Homeostasis 9%
• Carboxy Terminal Sequence 9%
• Virus Core 9%
• Biogenesis 9%
• Hepatoma Cell 9%
• Gene Amplification 9%