Degradation of ribosomal RNA during chicken lens development

William F. Zapisek; John Papaconstantinou

doi:10.1016/0005-2787(73)90233-5

Degradation of ribosomal RNA during chicken lens development

William F. Zapisek, John Papaconstantinou

Research output: Contribution to journal › Article

5 Scopus citations

Abstract

During the development of the vertebrate lens it acquires a low RNA content. Evidence indicates the persistence of a low molecular weight RNA while rRNA is depleted. This low molecular weight RNA has been characterized by chromatography, centrifugation and electrophoresis. Data indicate that it is primarily tRNA with small amounts of 5-S RNA. The persistence of the low molecular weight component is shown to be due to the selective retention of tRNA and not the accumulation of rRNA breakdown products. The degradation of rRNA is shown to occur on sedimentable ribonucleoprotein particles.

Original language	English (US)
Pages (from-to)	603-611
Number of pages	9
Journal	BBA Section Nucleic Acids And Protein Synthesis
Volume	299
Issue number	4
DOIs	https://doi.org/10.1016/0005-2787(73)90233-5
State	Published - Apr 11 1973
Externally published	Yes

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ASJC Scopus subject areas

Medicine(all)

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Zapisek, W. F., & Papaconstantinou, J. (1973). Degradation of ribosomal RNA during chicken lens development. BBA Section Nucleic Acids And Protein Synthesis, 299(4), 603-611. https://doi.org/10.1016/0005-2787(73)90233-5

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10.1016/0005-2787(73)90233-5