Abstract
During the development of the vertebrate lens it acquires a low RNA content. Evidence indicates the persistence of a low molecular weight RNA while rRNA is depleted. This low molecular weight RNA has been characterized by chromatography, centrifugation and electrophoresis. Data indicate that it is primarily tRNA with small amounts of 5-S RNA. The persistence of the low molecular weight component is shown to be due to the selective retention of tRNA and not the accumulation of rRNA breakdown products. The degradation of rRNA is shown to occur on sedimentable ribonucleoprotein particles.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 603-611 |
| Number of pages | 9 |
| Journal | BBA Section Nucleic Acids And Protein Synthesis |
| Volume | 299 |
| Issue number | 4 |
| DOIs | |
| State | Published - Apr 11 1973 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Medicine(all)
Cite this
Degradation of ribosomal RNA during chicken lens development. / Zapisek, William F.; Papaconstantinou, John.
In: BBA Section Nucleic Acids And Protein Synthesis, Vol. 299, No. 4, 11.04.1973, p. 603-611.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Degradation of ribosomal RNA during chicken lens development
AU - Zapisek, William F.
AU - Papaconstantinou, John
PY - 1973/4/11
Y1 - 1973/4/11
N2 - During the development of the vertebrate lens it acquires a low RNA content. Evidence indicates the persistence of a low molecular weight RNA while rRNA is depleted. This low molecular weight RNA has been characterized by chromatography, centrifugation and electrophoresis. Data indicate that it is primarily tRNA with small amounts of 5-S RNA. The persistence of the low molecular weight component is shown to be due to the selective retention of tRNA and not the accumulation of rRNA breakdown products. The degradation of rRNA is shown to occur on sedimentable ribonucleoprotein particles.
AB - During the development of the vertebrate lens it acquires a low RNA content. Evidence indicates the persistence of a low molecular weight RNA while rRNA is depleted. This low molecular weight RNA has been characterized by chromatography, centrifugation and electrophoresis. Data indicate that it is primarily tRNA with small amounts of 5-S RNA. The persistence of the low molecular weight component is shown to be due to the selective retention of tRNA and not the accumulation of rRNA breakdown products. The degradation of rRNA is shown to occur on sedimentable ribonucleoprotein particles.
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U2 - 10.1016/0005-2787(73)90233-5
DO - 10.1016/0005-2787(73)90233-5
M3 - Article
VL - 299
SP - 603
EP - 611
JO - BBA Section Nucleic Acids And Protein Synthesis
JF - BBA Section Nucleic Acids And Protein Synthesis
SN - 0005-2787
IS - 4
ER -