Degradation of ribosomal RNA during chicken lens development

William F. Zapisek, John Papaconstantinou

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

During the development of the vertebrate lens it acquires a low RNA content. Evidence indicates the persistence of a low molecular weight RNA while rRNA is depleted. This low molecular weight RNA has been characterized by chromatography, centrifugation and electrophoresis. Data indicate that it is primarily tRNA with small amounts of 5-S RNA. The persistence of the low molecular weight component is shown to be due to the selective retention of tRNA and not the accumulation of rRNA breakdown products. The degradation of rRNA is shown to occur on sedimentable ribonucleoprotein particles.

Original languageEnglish (US)
Pages (from-to)603-611
Number of pages9
JournalBBA Section Nucleic Acids And Protein Synthesis
Volume299
Issue number4
DOIs
StatePublished - Apr 11 1973
Externally publishedYes

Fingerprint

Ribosomal RNA
Lenses
Chickens
RNA
Molecular Weight
Transfer RNA
Ribonucleoproteins
Centrifugation
Vertebrates
Electrophoresis
Chromatography

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Degradation of ribosomal RNA during chicken lens development. / Zapisek, William F.; Papaconstantinou, John.

In: BBA Section Nucleic Acids And Protein Synthesis, Vol. 299, No. 4, 11.04.1973, p. 603-611.

Research output: Contribution to journalArticle

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