Deletion of braun lipoprotein and plasminogen-activating protease-encoding genes attenuates Yersinia pestis in mouse models of bubonic and pneumonic plague

Keyphrases

• Pneumonic Plague 100%
• Bubonic Plague 100%
• Yersinia Pestis 100%
• Mouse Model 100%
• Plasminogen 100%
• Protease 100%
• Braun Lipoprotein 100%
• Coding Genes 100%
• Lipoproteins 66%
• T Cells 33%
• Tumor Necrosis Factor-α 33%
• Protease Gene 33%
• Cellular Immunity 16%
• Humoral Immune Response 16%
• Humoral Immunity 16%
• Plague 16%
• Inflammatory Cytokines 16%
• Interleukin-4 (IL-4) 16%
• Lung 16%
• Liver 16%
• Live Attenuated Vaccine 16%
• Attenuated Vaccine Strains 16%
• FDA-approved Drugs 16%
• Proliferative Response 16%
• Mandatory Vaccines 16%
• Causative Agents 16%
• Infected Mice 16%
• CD4+ 16%
• CD8+ T Cells 16%
• Interferon-α (IFN-α) 16%
• Double mutant 16%
• Lethal Dose 16%
• Interferon-γ 16%
• Peripheral Organs 16%
• Intranasal 16%
• Damage Level 16%
• Specific Antigen 16%
• Y. Pestis 16%
• Immunized Animal 16%
• Isogenic mutants 16%
• Heat-killed 16%
• Subcutaneous Route 16%

Immunology and Microbiology

• Mouse Model 100%
• Yersinia Pestis 100%
• Lipoprotein 100%
• Proteinase 100%
• Protease 100%
• Wild Type 83%
• Humoral Immunity 33%
• T Cell 33%
• Tumor Necrosis Factor Alpha 33%
• Adoptive Immunity 16%
• Proinflammatory Cytokine 16%
• interferon 16%
• Antigen Specificity 16%
• T-Helper Cell 16%
• Attenuated Vaccine 16%
• Live Vaccine 16%
• Interleukin 4 16%
• Antigen 16%
• Cytotoxic T-Cell 16%
• Interferon Gamma 16%
• Sublethal Dose 16%
• Lung 16%
• Bacterium 16%

Pharmacology, Toxicology and Pharmaceutical Science

• Mouse Model 100%
• Pneumonic Plague 100%
• Yersinia Pestis 100%
• Bubonic Plague 100%
• Lipoprotein 100%
• Proteinase 100%
• Plasminogen 100%
• Antigen 33%
• Tumor Necrosis Factor 33%
• Vaccine Strain 16%
• Cytokine 16%
• Live Vaccine 16%
• Interferon 16%
• Gamma Interferon 16%
• Interleukin 4 16%
• CD8 Antigen 16%
• Subcutaneous Route 16%
• Bacterium 16%