Demographics of natural oral infection of mosquitos by venezuelan equine encephalitis virus

Serafín Gutiérrez, Gaël Thébaud, Darci R. Smith, Joan L. Kenney, Scott C. Weaver

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

The within-host diversity of virus populations can be drastically limited during between-host transmission, with primary infection of hosts representing a major constraint to diversity maintenance. However, there is an extreme paucity of quantitative data on the demographic changes experienced by virus populations during primary infection. Here, the multiplicity of cellular infection (MOI) and population bottlenecks were quantified during primary mosquito infection by Venezuelan equine encephalitis virus, an arbovirus causing neurological disease in humans and equids.

Original languageEnglish (US)
Pages (from-to)4020-4022
Number of pages3
JournalJournal of virology
Volume89
Issue number7
DOIs
StatePublished - 2015

ASJC Scopus subject areas

  • Microbiology
  • Immunology
  • Insect Science
  • Virology

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