Description of Streptococcus pneumoniae infections in burn patients

Jessie S. Glasser, Michael L. Landrum, Kevin K. Chung, Duane R. Hospenthal, Evan M. Renz, Steven Wolf, Clinton K. Murray

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Background: Longer survival in burn patients has resulted in more infectious complications, typically with Klebsiella pneumoniae, Pseudomonas aeruginosa, Acinetobacter baumannii, and Staphylococcus aureus. Although Streptococcus pneumoniae infections are common in the community and can cause nosocomial infections, the incidence and risk factors for pneumococcal infections in burn patients is unclear. Methods: We performed an electronic retrospective chart review to collect rates of and risk factors for S. pneumoniae infections in patients with thermal burns from March 2003 through June 2008. Results: Of the 1838 patients admitted to the burn center, 10 were infected (0.54% incidence). Patients presented with pneumonia (seven patients, 0.38% incidence) and bacteremia (three patients, 0.16% incidence) within a week of initial burn (median 1 day, range 0-8), often in the setting of bacterial co-infection (five patients). This group was mainly young males with median 28.8% total body surface area burns; 60% had concomitant inhalational injury. Most did not have traditional risk factors for pneumococcal infection but had objective signs of infection at time of positive culture and were treated with appropriate antibiotics. Two patients in this series died, although no mortality was attributed to S. pneumoniae. Conclusions: Pneumococcal disease is not common in burn patients and generally occurs early on in hospitalization after burn making it more likely to be a community-acquired pathogen rather than nosocomial in the burn population. It should be considered in the setting of sepsis or new pulmonary infiltrates within a week after burn, but typical empiric antibiotics against the usual burn pathogens should be adequate to also treat for pneumococcal infection.

Original languageEnglish (US)
Pages (from-to)528-532
Number of pages5
JournalBurns
Volume36
Issue number4
DOIs
StatePublished - Jun 1 2010
Externally publishedYes

Fingerprint

Pneumococcal Infections
Incidence
Burns
Anti-Bacterial Agents
Burn Units
Acinetobacter baumannii
Body Surface Area
Klebsiella pneumoniae
Cross Infection
Bacteremia
Streptococcus pneumoniae
Coinfection
Bacterial Infections
Pseudomonas aeruginosa
Staphylococcus aureus
Sepsis
Pneumonia
Hospitalization
Hot Temperature

Keywords

  • Burn
  • Pneumococcal
  • Pneumococcus
  • Streptococcus pneumoniae

ASJC Scopus subject areas

  • Surgery
  • Emergency Medicine
  • Critical Care and Intensive Care Medicine

Cite this

Glasser, J. S., Landrum, M. L., Chung, K. K., Hospenthal, D. R., Renz, E. M., Wolf, S., & Murray, C. K. (2010). Description of Streptococcus pneumoniae infections in burn patients. Burns, 36(4), 528-532. https://doi.org/10.1016/j.burns.2009.07.006

Description of Streptococcus pneumoniae infections in burn patients. / Glasser, Jessie S.; Landrum, Michael L.; Chung, Kevin K.; Hospenthal, Duane R.; Renz, Evan M.; Wolf, Steven; Murray, Clinton K.

In: Burns, Vol. 36, No. 4, 01.06.2010, p. 528-532.

Research output: Contribution to journalArticle

Glasser, JS, Landrum, ML, Chung, KK, Hospenthal, DR, Renz, EM, Wolf, S & Murray, CK 2010, 'Description of Streptococcus pneumoniae infections in burn patients', Burns, vol. 36, no. 4, pp. 528-532. https://doi.org/10.1016/j.burns.2009.07.006
Glasser JS, Landrum ML, Chung KK, Hospenthal DR, Renz EM, Wolf S et al. Description of Streptococcus pneumoniae infections in burn patients. Burns. 2010 Jun 1;36(4):528-532. https://doi.org/10.1016/j.burns.2009.07.006
Glasser, Jessie S. ; Landrum, Michael L. ; Chung, Kevin K. ; Hospenthal, Duane R. ; Renz, Evan M. ; Wolf, Steven ; Murray, Clinton K. / Description of Streptococcus pneumoniae infections in burn patients. In: Burns. 2010 ; Vol. 36, No. 4. pp. 528-532.
@article{101c63392dd54a66b2337dd161b3dac8,
title = "Description of Streptococcus pneumoniae infections in burn patients",
abstract = "Background: Longer survival in burn patients has resulted in more infectious complications, typically with Klebsiella pneumoniae, Pseudomonas aeruginosa, Acinetobacter baumannii, and Staphylococcus aureus. Although Streptococcus pneumoniae infections are common in the community and can cause nosocomial infections, the incidence and risk factors for pneumococcal infections in burn patients is unclear. Methods: We performed an electronic retrospective chart review to collect rates of and risk factors for S. pneumoniae infections in patients with thermal burns from March 2003 through June 2008. Results: Of the 1838 patients admitted to the burn center, 10 were infected (0.54{\%} incidence). Patients presented with pneumonia (seven patients, 0.38{\%} incidence) and bacteremia (three patients, 0.16{\%} incidence) within a week of initial burn (median 1 day, range 0-8), often in the setting of bacterial co-infection (five patients). This group was mainly young males with median 28.8{\%} total body surface area burns; 60{\%} had concomitant inhalational injury. Most did not have traditional risk factors for pneumococcal infection but had objective signs of infection at time of positive culture and were treated with appropriate antibiotics. Two patients in this series died, although no mortality was attributed to S. pneumoniae. Conclusions: Pneumococcal disease is not common in burn patients and generally occurs early on in hospitalization after burn making it more likely to be a community-acquired pathogen rather than nosocomial in the burn population. It should be considered in the setting of sepsis or new pulmonary infiltrates within a week after burn, but typical empiric antibiotics against the usual burn pathogens should be adequate to also treat for pneumococcal infection.",
keywords = "Burn, Pneumococcal, Pneumococcus, Streptococcus pneumoniae",
author = "Glasser, {Jessie S.} and Landrum, {Michael L.} and Chung, {Kevin K.} and Hospenthal, {Duane R.} and Renz, {Evan M.} and Steven Wolf and Murray, {Clinton K.}",
year = "2010",
month = "6",
day = "1",
doi = "10.1016/j.burns.2009.07.006",
language = "English (US)",
volume = "36",
pages = "528--532",
journal = "Burns",
issn = "0305-4179",
publisher = "Elsevier Limited",
number = "4",

}

TY - JOUR

T1 - Description of Streptococcus pneumoniae infections in burn patients

AU - Glasser, Jessie S.

AU - Landrum, Michael L.

AU - Chung, Kevin K.

AU - Hospenthal, Duane R.

AU - Renz, Evan M.

AU - Wolf, Steven

AU - Murray, Clinton K.

PY - 2010/6/1

Y1 - 2010/6/1

N2 - Background: Longer survival in burn patients has resulted in more infectious complications, typically with Klebsiella pneumoniae, Pseudomonas aeruginosa, Acinetobacter baumannii, and Staphylococcus aureus. Although Streptococcus pneumoniae infections are common in the community and can cause nosocomial infections, the incidence and risk factors for pneumococcal infections in burn patients is unclear. Methods: We performed an electronic retrospective chart review to collect rates of and risk factors for S. pneumoniae infections in patients with thermal burns from March 2003 through June 2008. Results: Of the 1838 patients admitted to the burn center, 10 were infected (0.54% incidence). Patients presented with pneumonia (seven patients, 0.38% incidence) and bacteremia (three patients, 0.16% incidence) within a week of initial burn (median 1 day, range 0-8), often in the setting of bacterial co-infection (five patients). This group was mainly young males with median 28.8% total body surface area burns; 60% had concomitant inhalational injury. Most did not have traditional risk factors for pneumococcal infection but had objective signs of infection at time of positive culture and were treated with appropriate antibiotics. Two patients in this series died, although no mortality was attributed to S. pneumoniae. Conclusions: Pneumococcal disease is not common in burn patients and generally occurs early on in hospitalization after burn making it more likely to be a community-acquired pathogen rather than nosocomial in the burn population. It should be considered in the setting of sepsis or new pulmonary infiltrates within a week after burn, but typical empiric antibiotics against the usual burn pathogens should be adequate to also treat for pneumococcal infection.

AB - Background: Longer survival in burn patients has resulted in more infectious complications, typically with Klebsiella pneumoniae, Pseudomonas aeruginosa, Acinetobacter baumannii, and Staphylococcus aureus. Although Streptococcus pneumoniae infections are common in the community and can cause nosocomial infections, the incidence and risk factors for pneumococcal infections in burn patients is unclear. Methods: We performed an electronic retrospective chart review to collect rates of and risk factors for S. pneumoniae infections in patients with thermal burns from March 2003 through June 2008. Results: Of the 1838 patients admitted to the burn center, 10 were infected (0.54% incidence). Patients presented with pneumonia (seven patients, 0.38% incidence) and bacteremia (three patients, 0.16% incidence) within a week of initial burn (median 1 day, range 0-8), often in the setting of bacterial co-infection (five patients). This group was mainly young males with median 28.8% total body surface area burns; 60% had concomitant inhalational injury. Most did not have traditional risk factors for pneumococcal infection but had objective signs of infection at time of positive culture and were treated with appropriate antibiotics. Two patients in this series died, although no mortality was attributed to S. pneumoniae. Conclusions: Pneumococcal disease is not common in burn patients and generally occurs early on in hospitalization after burn making it more likely to be a community-acquired pathogen rather than nosocomial in the burn population. It should be considered in the setting of sepsis or new pulmonary infiltrates within a week after burn, but typical empiric antibiotics against the usual burn pathogens should be adequate to also treat for pneumococcal infection.

KW - Burn

KW - Pneumococcal

KW - Pneumococcus

KW - Streptococcus pneumoniae

UR - http://www.scopus.com/inward/record.url?scp=77950519665&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77950519665&partnerID=8YFLogxK

U2 - 10.1016/j.burns.2009.07.006

DO - 10.1016/j.burns.2009.07.006

M3 - Article

C2 - 19765906

AN - SCOPUS:77950519665

VL - 36

SP - 528

EP - 532

JO - Burns

JF - Burns

SN - 0305-4179

IS - 4

ER -