Detection and characterization of bat sarbecovirus phylogenetically related to SARS-CoV-2, Japan

Shin Murakami; Tomoya Kitamura; Jin Suzuki; Ryouta Sato; Toshiki Aoi; Marina Fujii; Hiromichi Matsugo; Haruhiko Kamiki; Hiroho Ishida; Akiko Takenaka-Uema; Masayuki Shimojima; Taisuke Horimoto

doi:10.3368/CL.60.4.598

Detection and characterization of bat sarbecovirus phylogenetically related to SARS-CoV-2, Japan

Shin Murakami, Tomoya Kitamura, Jin Suzuki, Ryouta Sato, Toshiki Aoi, Marina Fujii, Hiromichi Matsugo, Haruhiko Kamiki, Hiroho Ishida, Akiko Takenaka-Uema, Masayuki Shimojima, Taisuke Horimoto

Research output: Contribution to journal › Article › peer-review

108 Scopus citations

Abstract

Epidemiology of bat Betacoronavirus, subgenus Sarbecovirus is largely unknown, especially outside China. We detected a sarbecovirus phylogenetically related to severe acute respiratory syndrome coronavirus 2 from Rhinolophus cornutus bats in Japan. The sarbecovirus' spike protein specifically recognizes angiotensin-converting enzyme 2 of R. cornutus, but not humans, as an entry receptor.

Original language	English (US)
Pages (from-to)	3025-3029
Number of pages	5
Journal	Emerging infectious diseases
Volume	26
Issue number	12
DOIs	https://doi.org/10.3368/CL.60.4.598
State	Published - Dec 2020
Externally published	Yes

ASJC Scopus subject areas

Epidemiology
Microbiology (medical)
Infectious Diseases

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title = "Detection and characterization of bat sarbecovirus phylogenetically related to SARS-CoV-2, Japan",

abstract = "Epidemiology of bat Betacoronavirus, subgenus Sarbecovirus is largely unknown, especially outside China. We detected a sarbecovirus phylogenetically related to severe acute respiratory syndrome coronavirus 2 from Rhinolophus cornutus bats in Japan. The sarbecovirus' spike protein specifically recognizes angiotensin-converting enzyme 2 of R. cornutus, but not humans, as an entry receptor.",

author = "Shin Murakami and Tomoya Kitamura and Jin Suzuki and Ryouta Sato and Toshiki Aoi and Marina Fujii and Hiromichi Matsugo and Haruhiko Kamiki and Hiroho Ishida and Akiko Takenaka-Uema and Masayuki Shimojima and Taisuke Horimoto",

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doi = "10.3368/CL.60.4.598",

language = "English (US)",

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T1 - Detection and characterization of bat sarbecovirus phylogenetically related to SARS-CoV-2, Japan

AU - Murakami, Shin

AU - Kitamura, Tomoya

AU - Suzuki, Jin

AU - Sato, Ryouta

AU - Aoi, Toshiki

AU - Fujii, Marina

AU - Matsugo, Hiromichi

AU - Kamiki, Haruhiko

AU - Ishida, Hiroho

AU - Takenaka-Uema, Akiko

AU - Shimojima, Masayuki

AU - Horimoto, Taisuke

PY - 2020/12

Y1 - 2020/12

N2 - Epidemiology of bat Betacoronavirus, subgenus Sarbecovirus is largely unknown, especially outside China. We detected a sarbecovirus phylogenetically related to severe acute respiratory syndrome coronavirus 2 from Rhinolophus cornutus bats in Japan. The sarbecovirus' spike protein specifically recognizes angiotensin-converting enzyme 2 of R. cornutus, but not humans, as an entry receptor.

AB - Epidemiology of bat Betacoronavirus, subgenus Sarbecovirus is largely unknown, especially outside China. We detected a sarbecovirus phylogenetically related to severe acute respiratory syndrome coronavirus 2 from Rhinolophus cornutus bats in Japan. The sarbecovirus' spike protein specifically recognizes angiotensin-converting enzyme 2 of R. cornutus, but not humans, as an entry receptor.

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ER -

Detection and characterization of bat sarbecovirus phylogenetically related to SARS-CoV-2, Japan

Abstract

ASJC Scopus subject areas

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