Detection of Mycobacterium tuberculosis in latently infected lungs by immunohistochemistry and confocal microscopy

Selvakumar Subbian, Eliseo Eugenin, Gilla Kaplan

Research output: Contribution to journalArticle

9 Scopus citations


Detection of latent Mycobacterium tuberculosis is a challenge in the diagnosis of asymptomatic, subclinical tuberculosis. We report the development of an immunofluorescence technique to visualize and enumerate M. tuberculosis in latently infected rabbit lungs where no acid-fast– stained organisms were seen and no cultivable bacilli were obtained by the agar-plating method.

Original languageEnglish (US)
Article number081091
Pages (from-to)1432-1435
Number of pages4
JournalJournal of Medical Microbiology
StatePublished - Nov 1 2014
Externally publishedYes


ASJC Scopus subject areas

  • Microbiology
  • Microbiology (medical)

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