Determination of atrazine in water at low- and sub-parts-per-trillion levels by using solid-phase extraction and gas chromatography/high-resolution mass spectrometry

Zongwei Cai, V-M Ramanujam, Daryl E. Giblin, Michael L. Gross, Roy F. Spalding

Research output: Contribution to journalArticle

57 Citations (Scopus)

Abstract

A capillary column gas chromatography/high-resolution mass spectrometry (GC/HRMS) method was developed to determine atrazine in water at low- and sub-parts-per-trillion (ppt) levels. The method fills a need when the detection limits of routine GC, GC/MS, and high-performance liquid chromatography (HPLC) are inadequate for studies to evaluate transport and fate of herbicides in deep ground water systems. Atrazlne and the added internal standard [13C3]atrazine were extracted from water samples by solid-phase extraction using a C18 bonded silica cartridge. A column chromatography procedure with Florisll was developed to reduce when necessary further interferences in the sample extract. The analysis was performed by GC/HRMS with the mass spectrometer operated in the selected ion monitoring (SIM) mode; mass profiles were acquired. The precision and accuracy of the method are 15% (relative standard deviation, n = 8) and >85%, respectively, for standard water samples containing atrazine at 1 ppt. The method, which gives detection limits of 200-500 parts-per-quadrillion (ppq), has been successfully used to analyze water samples containing atrazine at concentration levels of 1-500 ppt.

Original languageEnglish (US)
Pages (from-to)21-26
Number of pages6
JournalAnalytical Chemistry
Volume65
Issue number1
StatePublished - Jan 1 1993
Externally publishedYes

Fingerprint

Atrazine
Gas chromatography
Mass spectrometry
Column chromatography
Water
High performance liquid chromatography
Herbicides
Mass spectrometers
Silicon Dioxide
Groundwater
Ions
Monitoring

ASJC Scopus subject areas

  • Analytical Chemistry

Cite this

Determination of atrazine in water at low- and sub-parts-per-trillion levels by using solid-phase extraction and gas chromatography/high-resolution mass spectrometry. / Cai, Zongwei; Ramanujam, V-M; Giblin, Daryl E.; Gross, Michael L.; Spalding, Roy F.

In: Analytical Chemistry, Vol. 65, No. 1, 01.01.1993, p. 21-26.

Research output: Contribution to journalArticle

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abstract = "A capillary column gas chromatography/high-resolution mass spectrometry (GC/HRMS) method was developed to determine atrazine in water at low- and sub-parts-per-trillion (ppt) levels. The method fills a need when the detection limits of routine GC, GC/MS, and high-performance liquid chromatography (HPLC) are inadequate for studies to evaluate transport and fate of herbicides in deep ground water systems. Atrazlne and the added internal standard [13C3]atrazine were extracted from water samples by solid-phase extraction using a C18 bonded silica cartridge. A column chromatography procedure with Florisll was developed to reduce when necessary further interferences in the sample extract. The analysis was performed by GC/HRMS with the mass spectrometer operated in the selected ion monitoring (SIM) mode; mass profiles were acquired. The precision and accuracy of the method are 15{\%} (relative standard deviation, n = 8) and >85{\%}, respectively, for standard water samples containing atrazine at 1 ppt. The method, which gives detection limits of 200-500 parts-per-quadrillion (ppq), has been successfully used to analyze water samples containing atrazine at concentration levels of 1-500 ppt.",
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