Determination of cardiac output and other reference physiology parameters in lightly anesthetized dogs

John H. Cissik, William J. Ehler, Gary D. Hankins, John C. Hauth, Wayne A. Pierson

Research output: Contribution to journalArticle

5 Scopus citations

Abstract

1. 1. Cardiac output; arterial, pulmonary artery, central venous and pulmonary wedge pressures; heart rate, hematocrit, and plasma sodium and potassium; arterial and mixed venous blood gases; and respiratory rates were measured in 45 mixed sex, non-pregnant, clinically normal mongrel dogs of 8-30 kilograms body weight following light anesthesia with halothane/50% N20-02. 2. 2. Arithmetic means and standard deviations were calculated to develop tables of reference values. 3. 3. Mean measured cardiac outputs were found to be 31-59% higher in these dogs than the values indicated by published standards; cardiac indices were 30-44% higher; heart rates were 16-30% lower; calculated stroke volumes were 60-112% greater; and total peripheral resistances were 35-57% less than the standard published values. 4. 4. All other measured or calculated parameters fell within previously published canine or human reference limits.

Original languageEnglish (US)
Pages (from-to)89-93
Number of pages5
JournalComparative Biochemistry and Physiology -- Part A: Physiology
Volume88
Issue number1
DOIs
StatePublished - 1987

ASJC Scopus subject areas

  • Physiology

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