@inproceedings{d1eeec6e8c4a42f08dec899e8af1ecb6,
title = "Deterministic modeling of interferon-beta signaling pathway",
abstract = "The paper is concerned with dynamical modeling of early and late gene expression in one of Interferon-β induced signaling pathways. First, the biological background is given. Subsequently, the importance of stochastic nature of biological processes is addressed. Then, the assumptions underlying their deterministic modeling are presented and the mathematical model is introduced. Finally, the methodology for identification of model parameters is briefly described, followed by the presentation of experimental and simulation results. In addition to analysis of the particular regulatory network, this work also builds a framework for modeling of other signalling pathways whose not all components are known.",
keywords = "Biocybernetics, Biomedical systems, Dynamic modelling, Feedback systems",
author = "Jaroslaw Smieja and Mohammad Jamaluddin and Allan Brasier and Marek Kimmel",
note = "Funding Information: 1Partially supported by NHLBI Contract N01-HV-28184, Proteomic technologies in airway inflammation (A. Kurosky, P.I.) and by KBN (Polish Committee for Scientific Research) Grant No. 3T11 A02928",
year = "2006",
doi = "10.3182/20060920-3-fr-2912.00076",
language = "English (US)",
isbn = "9783902661180",
series = "IFAC Proceedings Volumes (IFAC-PapersOnline)",
publisher = "IFAC Secretariat",
number = "PART 1",
pages = "423--428",
booktitle = "6th IFAC Symposium on Modeling and Control in Biomedical Systems, MCBMS 2006",
address = "Austria",
edition = "PART 1",
}