Development of a device for measuring adherence of skin grafts to the wound surface

C. Dong, E. Mead, R. Skalak, Y. C. Fung, J. C. Debes, Ramon Zapata Sirvent, C. Andree, G. Greenleaf, M. Cooper, J. F. Hansbrough

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Adherence of a biological graft to the wound surface is the most important factor influencing the ultimate success of graft viability. A machine has been developed to test the adherence of biological graft materials to a substrate such as a wound surface. The peeling mode, which yields reproducible quantitative measurements of adherence, is a standard method for testing adhesives. The device is designed to continuously measure the force required to peel the graft from the substrate at a constant rate. This force is a function of the energy of adhesion per unit area of adhered surface. This device has been used to measure the peeling force of (2×2 cm) skin grafts which are applied to full-thickness wounds on mice. Results of tests on adherence of autografts on mice show that the peeling force increases significantly with time over the first 9 days of healing. Thus, this device is useful in quantitative comparison of various skin grafting techniques and artificial grafts.

Original languageEnglish (US)
Pages (from-to)51-55
Number of pages5
JournalAnnals of Biomedical Engineering
Volume21
Issue number1
DOIs
StatePublished - Jan 1 1993
Externally publishedYes

Fingerprint

Grafts
Skin
Peeling
Substrates
Adhesives
Adhesion
Testing

Keywords

  • Adherence
  • Skin grafts
  • Tensiometer

ASJC Scopus subject areas

  • Biomedical Engineering

Cite this

Development of a device for measuring adherence of skin grafts to the wound surface. / Dong, C.; Mead, E.; Skalak, R.; Fung, Y. C.; Debes, J. C.; Zapata Sirvent, Ramon; Andree, C.; Greenleaf, G.; Cooper, M.; Hansbrough, J. F.

In: Annals of Biomedical Engineering, Vol. 21, No. 1, 01.01.1993, p. 51-55.

Research output: Contribution to journalArticle

Dong, C, Mead, E, Skalak, R, Fung, YC, Debes, JC, Zapata Sirvent, R, Andree, C, Greenleaf, G, Cooper, M & Hansbrough, JF 1993, 'Development of a device for measuring adherence of skin grafts to the wound surface', Annals of Biomedical Engineering, vol. 21, no. 1, pp. 51-55. https://doi.org/10.1007/BF02368164
Dong, C. ; Mead, E. ; Skalak, R. ; Fung, Y. C. ; Debes, J. C. ; Zapata Sirvent, Ramon ; Andree, C. ; Greenleaf, G. ; Cooper, M. ; Hansbrough, J. F. / Development of a device for measuring adherence of skin grafts to the wound surface. In: Annals of Biomedical Engineering. 1993 ; Vol. 21, No. 1. pp. 51-55.
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