Development of an experimental hairless guinea pig model for testing ethyl alcohol-associated phototoxicity

Jennifer A. Ray, Maribel I. Colome, Richard F. Wagner

Research output: Contribution to journalArticle

Abstract

In theory, excess ingestion of ethyl alcohol may alter normal porphyrin metabolism through liver damage. A hairless guinea pig model was used to test this hypothesis. Although the initial experimental results were inconclusive, this novel animal model may prove useful for future research about the possible role of ethyl alcohol in phototoxicity and sunburn.

Original languageEnglish (US)
Pages (from-to)25-37
Number of pages13
JournalSkin Cancer
Volume23
Issue number1
StatePublished - Jan 1 2008

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Keywords

  • Ethyl alcohol
  • Guinea pig
  • Phototoxicity
  • Porphyrins
  • Solar simulator
  • Sunburn

ASJC Scopus subject areas

  • Oncology
  • Dermatology

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