Diacerein is a potent and selective inhibitor of palmitoylethanolamide inactivation with analgesic activity in a rat model of acute inflammatory pain

Keyphrases

• Selective Inhibitor 100%
• Rat Model 100%
• Chronic Inflammatory Pain 100%
• Potent Inhibitor 100%
• Palmitoylethanolamide 100%
• Analgesic Activity 100%
• N-acylethanolamine-hydrolyzing Acid Amidase 100%
• Diacerein 100%
• Inflammation 20%
• Recombinant 20%
• Inhibitory Activity 20%
• Analgesic 20%
• Endogenous Levels 20%
• Mammalian Cells 20%
• Hyperalgesia 20%
• Triethanolamine 20%
• Hydrolysis 20%
• Enzymatic Hydrolysis 20%
• Anti-inflammatory Activity 20%
• Palmitoyl-CoA 20%
• Palmitic Acid 20%
• Carboxylic Acids 20%
• HEK293 Cells 20%
• Dioxo 20%
• Carrageenan 20%
• Anthracene 20%
• Lysosomal Enzymes 20%
• Phosphatidylethanolamine 20%
• Biosynthetic Precursor 20%
• Potential Inhibitors 20%
• Fatty Acid Amide Hydrolase 20%
• Paw Skin 20%

Medicine and Dentistry

• Inflammatory Pain 100%
• Analgesic Activity 100%
• Palmitoylethanolamide 100%
• Diacerein 100%
• Amidase 100%
• Enzymatic Hydrolysis 40%
• Anodyne 20%
• Precursor 20%
• Hyperpathia 20%
• Palmitic Acid 20%
• Intraplantar Drug Administration 20%
• Mammalian Cell 20%
• Antiinflammatory Activity 20%
• Lysosome Enzyme 20%
• Recombinant 20%
• Carrageenan 20%
• Phosphatidylethanolamine 20%
• Anthracene 20%
• Paw Skin 20%
• Carboxylic Acid 20%
• Fatty Acid Amidase 20%
• Ethanolamine 20%

Pharmacology, Toxicology and Pharmaceutical Science

• Rat Model 100%
• Inflammatory Pain 100%
• Analgesic Agent 100%
• Amidase 100%
• Palmitoylethanolamide 100%
• Diacerein 100%
• Palmitic Acid 20%
• Inflammation 20%
• Recombinant 20%
• Anti-Inflammatory Drug 20%
• Hyperalgesia 20%
• Carboxylate 20%
• Carrageenan 20%
• Anthracene 20%
• Phosphatidylethanolamine 20%
• Lysosome Enzyme 20%
• Fatty Acid Amidase 20%
• Ethanolamine 20%