Diagnostic assessment of normal and pale optic nerve heads by confocal scanning laser ophthalmoscope and stereophotography

Paolo Fogagnolo, Simona Romano, Stefano Ranno, Giovanni Taibbi, Chiara Pierrottet, Antonio Ferreras, Michele Figus, Luca Rossetti, Nicola Orzalesi

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Purpose: To evaluate the diagnostic assessment of optic nerve heads (ONH) by stereophotography (SP) and Heidelberg retina tomograph (HRT) in patients with retinitis pigmentosa (RP). Methods: This study involved 53 consecutive patients with RP and 24 controls who underwent ONH examination by SP and HRT. On the basis of the appearance at SP, RP ONH were divided in normal-colored (24/53) and pale (29/53). The measurements of vertical ONH diameter and vertical cup/disc ratio (VCDR) by SP and HRT were compared between the groups by means of t test and Bland-Altman plots. Diagnosis, ONH pallor and size, HRT image quality (image standard deviation, SD) were also inspected as sources of differences in the results by means of a multivariate analysis. Results: Vertical diameter measurements were similar using SP and HRT, respectively (1.93 ± 0.50 and 1.80 ± 0.62 for normal-colored ONH, P=0.43; 2.02 ± 0.65 and 1.90 ± 0.40 for pale ONH, P=0.27; and 1.98 ± 0.55 and 1.84 ± 0.52 for controls, P=0.33). In normal-colored ONH, VCDR was 0.30 ± 0.11 at SP and 0.31 ± 0.21 at HRT (P=0.90); in controls, it was 0.29 ± 0.13 at SP and 0.30 ± 0.18 at HRT (P=0.77). In the group with pale ONH, VCDR was 0.34 ± 0.14 at SP and 0.53 ± 0.24 at HRT (P

Original languageEnglish (US)
Pages (from-to)10-14
Number of pages5
JournalJournal of Glaucoma
Volume20
Issue number1
DOIs
StatePublished - Jan 2011
Externally publishedYes

Fingerprint

Ophthalmoscopes
Optic Disk
Lasers
Retina
Retinitis Pigmentosa
Pallor
Multivariate Analysis

Keywords

  • confocal scanning laser ophthalmoscope
  • cup/disc ratio
  • glaucoma
  • HRT
  • image quality
  • neuropathy
  • paleness
  • pallor
  • retina tomography
  • stereophotography

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Diagnostic assessment of normal and pale optic nerve heads by confocal scanning laser ophthalmoscope and stereophotography. / Fogagnolo, Paolo; Romano, Simona; Ranno, Stefano; Taibbi, Giovanni; Pierrottet, Chiara; Ferreras, Antonio; Figus, Michele; Rossetti, Luca; Orzalesi, Nicola.

In: Journal of Glaucoma, Vol. 20, No. 1, 01.2011, p. 10-14.

Research output: Contribution to journalArticle

Fogagnolo, P, Romano, S, Ranno, S, Taibbi, G, Pierrottet, C, Ferreras, A, Figus, M, Rossetti, L & Orzalesi, N 2011, 'Diagnostic assessment of normal and pale optic nerve heads by confocal scanning laser ophthalmoscope and stereophotography', Journal of Glaucoma, vol. 20, no. 1, pp. 10-14. https://doi.org/10.1097/IJG.0b013e3181d1d221
Fogagnolo, Paolo ; Romano, Simona ; Ranno, Stefano ; Taibbi, Giovanni ; Pierrottet, Chiara ; Ferreras, Antonio ; Figus, Michele ; Rossetti, Luca ; Orzalesi, Nicola. / Diagnostic assessment of normal and pale optic nerve heads by confocal scanning laser ophthalmoscope and stereophotography. In: Journal of Glaucoma. 2011 ; Vol. 20, No. 1. pp. 10-14.
@article{c2eb83d9e0fb49ad8d52d3f947546bac,
title = "Diagnostic assessment of normal and pale optic nerve heads by confocal scanning laser ophthalmoscope and stereophotography",
abstract = "Purpose: To evaluate the diagnostic assessment of optic nerve heads (ONH) by stereophotography (SP) and Heidelberg retina tomograph (HRT) in patients with retinitis pigmentosa (RP). Methods: This study involved 53 consecutive patients with RP and 24 controls who underwent ONH examination by SP and HRT. On the basis of the appearance at SP, RP ONH were divided in normal-colored (24/53) and pale (29/53). The measurements of vertical ONH diameter and vertical cup/disc ratio (VCDR) by SP and HRT were compared between the groups by means of t test and Bland-Altman plots. Diagnosis, ONH pallor and size, HRT image quality (image standard deviation, SD) were also inspected as sources of differences in the results by means of a multivariate analysis. Results: Vertical diameter measurements were similar using SP and HRT, respectively (1.93 ± 0.50 and 1.80 ± 0.62 for normal-colored ONH, P=0.43; 2.02 ± 0.65 and 1.90 ± 0.40 for pale ONH, P=0.27; and 1.98 ± 0.55 and 1.84 ± 0.52 for controls, P=0.33). In normal-colored ONH, VCDR was 0.30 ± 0.11 at SP and 0.31 ± 0.21 at HRT (P=0.90); in controls, it was 0.29 ± 0.13 at SP and 0.30 ± 0.18 at HRT (P=0.77). In the group with pale ONH, VCDR was 0.34 ± 0.14 at SP and 0.53 ± 0.24 at HRT (P",
keywords = "confocal scanning laser ophthalmoscope, cup/disc ratio, glaucoma, HRT, image quality, neuropathy, paleness, pallor, retina tomography, stereophotography",
author = "Paolo Fogagnolo and Simona Romano and Stefano Ranno and Giovanni Taibbi and Chiara Pierrottet and Antonio Ferreras and Michele Figus and Luca Rossetti and Nicola Orzalesi",
year = "2011",
month = "1",
doi = "10.1097/IJG.0b013e3181d1d221",
language = "English (US)",
volume = "20",
pages = "10--14",
journal = "Journal of Glaucoma",
issn = "1057-0829",
publisher = "Lippincott Williams and Wilkins",
number = "1",

}

TY - JOUR

T1 - Diagnostic assessment of normal and pale optic nerve heads by confocal scanning laser ophthalmoscope and stereophotography

AU - Fogagnolo, Paolo

AU - Romano, Simona

AU - Ranno, Stefano

AU - Taibbi, Giovanni

AU - Pierrottet, Chiara

AU - Ferreras, Antonio

AU - Figus, Michele

AU - Rossetti, Luca

AU - Orzalesi, Nicola

PY - 2011/1

Y1 - 2011/1

N2 - Purpose: To evaluate the diagnostic assessment of optic nerve heads (ONH) by stereophotography (SP) and Heidelberg retina tomograph (HRT) in patients with retinitis pigmentosa (RP). Methods: This study involved 53 consecutive patients with RP and 24 controls who underwent ONH examination by SP and HRT. On the basis of the appearance at SP, RP ONH were divided in normal-colored (24/53) and pale (29/53). The measurements of vertical ONH diameter and vertical cup/disc ratio (VCDR) by SP and HRT were compared between the groups by means of t test and Bland-Altman plots. Diagnosis, ONH pallor and size, HRT image quality (image standard deviation, SD) were also inspected as sources of differences in the results by means of a multivariate analysis. Results: Vertical diameter measurements were similar using SP and HRT, respectively (1.93 ± 0.50 and 1.80 ± 0.62 for normal-colored ONH, P=0.43; 2.02 ± 0.65 and 1.90 ± 0.40 for pale ONH, P=0.27; and 1.98 ± 0.55 and 1.84 ± 0.52 for controls, P=0.33). In normal-colored ONH, VCDR was 0.30 ± 0.11 at SP and 0.31 ± 0.21 at HRT (P=0.90); in controls, it was 0.29 ± 0.13 at SP and 0.30 ± 0.18 at HRT (P=0.77). In the group with pale ONH, VCDR was 0.34 ± 0.14 at SP and 0.53 ± 0.24 at HRT (P

AB - Purpose: To evaluate the diagnostic assessment of optic nerve heads (ONH) by stereophotography (SP) and Heidelberg retina tomograph (HRT) in patients with retinitis pigmentosa (RP). Methods: This study involved 53 consecutive patients with RP and 24 controls who underwent ONH examination by SP and HRT. On the basis of the appearance at SP, RP ONH were divided in normal-colored (24/53) and pale (29/53). The measurements of vertical ONH diameter and vertical cup/disc ratio (VCDR) by SP and HRT were compared between the groups by means of t test and Bland-Altman plots. Diagnosis, ONH pallor and size, HRT image quality (image standard deviation, SD) were also inspected as sources of differences in the results by means of a multivariate analysis. Results: Vertical diameter measurements were similar using SP and HRT, respectively (1.93 ± 0.50 and 1.80 ± 0.62 for normal-colored ONH, P=0.43; 2.02 ± 0.65 and 1.90 ± 0.40 for pale ONH, P=0.27; and 1.98 ± 0.55 and 1.84 ± 0.52 for controls, P=0.33). In normal-colored ONH, VCDR was 0.30 ± 0.11 at SP and 0.31 ± 0.21 at HRT (P=0.90); in controls, it was 0.29 ± 0.13 at SP and 0.30 ± 0.18 at HRT (P=0.77). In the group with pale ONH, VCDR was 0.34 ± 0.14 at SP and 0.53 ± 0.24 at HRT (P

KW - confocal scanning laser ophthalmoscope

KW - cup/disc ratio

KW - glaucoma

KW - HRT

KW - image quality

KW - neuropathy

KW - paleness

KW - pallor

KW - retina tomography

KW - stereophotography

UR - http://www.scopus.com/inward/record.url?scp=78651421521&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=78651421521&partnerID=8YFLogxK

U2 - 10.1097/IJG.0b013e3181d1d221

DO - 10.1097/IJG.0b013e3181d1d221

M3 - Article

VL - 20

SP - 10

EP - 14

JO - Journal of Glaucoma

JF - Journal of Glaucoma

SN - 1057-0829

IS - 1

ER -