Dietary protein recommendations and the prevention of sarcopenia

Research output: Contribution to journalArticle

409 Citations (Scopus)

Abstract

Purpose of review: To draw attention to recent work on the role of protein and the amount of protein needed with each meal to preserve skeletal muscle mass in ageing. Recent findings: Ageing does not inevitably reduce the anabolic response to a high-quality protein meal. Ingestion of approximately 25-30 g of protein per meal maximally stimulates muscle protein synthesis in both young and older individuals. However, muscle protein synthesis is blunted in elderly when protein and carbohydrate are coingested or when the quantity of protein is less than approximately 20 g per meal. Supplementing regular mixed-nutrient meals with leucine may also enhance the muscle protein synthetic response in elders. Summary: On the basis of recent work, we propose a novel and specific dietary approach to prevent or slow down muscle loss with ageing. Rather than recommending a large, global increase in the recommended dietary allowance (RDA) for protein for all elderly individuals, clinicians should stress the importance of ingesting a sufficient amount of protein with each meal. To maximize muscle protein synthesis while being cognizant of total energy intake, we propose a dietary plan that includes 25-30 g of high quality protein per meal.

Original languageEnglish (US)
Pages (from-to)86-90
Number of pages5
JournalCurrent Opinion in Clinical Nutrition and Metabolic Care
Volume12
Issue number1
DOIs
StatePublished - Jan 2009

Fingerprint

Sarcopenia
Dietary Proteins
Meals
Muscle Proteins
Proteins
Recommended Dietary Allowances
Energy Intake
Leucine
Skeletal Muscle
Eating
Carbohydrates
Food
Muscles

Keywords

  • Ageing
  • Leucine
  • Muscle protein synthesis
  • Protein intake
  • Sarcopenia

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Nutrition and Dietetics

Cite this

@article{cd5c9b9e480c46d09e64dde94b66376d,
title = "Dietary protein recommendations and the prevention of sarcopenia",
abstract = "Purpose of review: To draw attention to recent work on the role of protein and the amount of protein needed with each meal to preserve skeletal muscle mass in ageing. Recent findings: Ageing does not inevitably reduce the anabolic response to a high-quality protein meal. Ingestion of approximately 25-30 g of protein per meal maximally stimulates muscle protein synthesis in both young and older individuals. However, muscle protein synthesis is blunted in elderly when protein and carbohydrate are coingested or when the quantity of protein is less than approximately 20 g per meal. Supplementing regular mixed-nutrient meals with leucine may also enhance the muscle protein synthetic response in elders. Summary: On the basis of recent work, we propose a novel and specific dietary approach to prevent or slow down muscle loss with ageing. Rather than recommending a large, global increase in the recommended dietary allowance (RDA) for protein for all elderly individuals, clinicians should stress the importance of ingesting a sufficient amount of protein with each meal. To maximize muscle protein synthesis while being cognizant of total energy intake, we propose a dietary plan that includes 25-30 g of high quality protein per meal.",
keywords = "Ageing, Leucine, Muscle protein synthesis, Protein intake, Sarcopenia",
author = "Douglas Paddon-Jones and Blake Rasmussen",
year = "2009",
month = "1",
doi = "10.1097/MCO.0b013e32831cef8b",
language = "English (US)",
volume = "12",
pages = "86--90",
journal = "Current Opinion in Clinical Nutrition and Metabolic Care",
issn = "1363-1950",
publisher = "Lippincott Williams and Wilkins",
number = "1",

}

TY - JOUR

T1 - Dietary protein recommendations and the prevention of sarcopenia

AU - Paddon-Jones, Douglas

AU - Rasmussen, Blake

PY - 2009/1

Y1 - 2009/1

N2 - Purpose of review: To draw attention to recent work on the role of protein and the amount of protein needed with each meal to preserve skeletal muscle mass in ageing. Recent findings: Ageing does not inevitably reduce the anabolic response to a high-quality protein meal. Ingestion of approximately 25-30 g of protein per meal maximally stimulates muscle protein synthesis in both young and older individuals. However, muscle protein synthesis is blunted in elderly when protein and carbohydrate are coingested or when the quantity of protein is less than approximately 20 g per meal. Supplementing regular mixed-nutrient meals with leucine may also enhance the muscle protein synthetic response in elders. Summary: On the basis of recent work, we propose a novel and specific dietary approach to prevent or slow down muscle loss with ageing. Rather than recommending a large, global increase in the recommended dietary allowance (RDA) for protein for all elderly individuals, clinicians should stress the importance of ingesting a sufficient amount of protein with each meal. To maximize muscle protein synthesis while being cognizant of total energy intake, we propose a dietary plan that includes 25-30 g of high quality protein per meal.

AB - Purpose of review: To draw attention to recent work on the role of protein and the amount of protein needed with each meal to preserve skeletal muscle mass in ageing. Recent findings: Ageing does not inevitably reduce the anabolic response to a high-quality protein meal. Ingestion of approximately 25-30 g of protein per meal maximally stimulates muscle protein synthesis in both young and older individuals. However, muscle protein synthesis is blunted in elderly when protein and carbohydrate are coingested or when the quantity of protein is less than approximately 20 g per meal. Supplementing regular mixed-nutrient meals with leucine may also enhance the muscle protein synthetic response in elders. Summary: On the basis of recent work, we propose a novel and specific dietary approach to prevent or slow down muscle loss with ageing. Rather than recommending a large, global increase in the recommended dietary allowance (RDA) for protein for all elderly individuals, clinicians should stress the importance of ingesting a sufficient amount of protein with each meal. To maximize muscle protein synthesis while being cognizant of total energy intake, we propose a dietary plan that includes 25-30 g of high quality protein per meal.

KW - Ageing

KW - Leucine

KW - Muscle protein synthesis

KW - Protein intake

KW - Sarcopenia

UR - http://www.scopus.com/inward/record.url?scp=58149133630&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=58149133630&partnerID=8YFLogxK

U2 - 10.1097/MCO.0b013e32831cef8b

DO - 10.1097/MCO.0b013e32831cef8b

M3 - Article

VL - 12

SP - 86

EP - 90

JO - Current Opinion in Clinical Nutrition and Metabolic Care

JF - Current Opinion in Clinical Nutrition and Metabolic Care

SN - 1363-1950

IS - 1

ER -