Differential expression of muscle damage in humans following acute fast and slow velocity eccentric exercise

Douglas Paddon-Jones, A. Keech, A. Lonergan, P. Abernethy

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

We sought to determine if the velocity of an acute bout of eccentric contractions influenced the duration and severity of several common indirect markers of muscle damage. Subjects performed 36 maximal fast (FST, n=8: 3.14 rad·s-1) or slow (SLW, n=7: 0.52 rad·s-1) velocity isokinetic eccentric contractions with the elbow flexors of the non-dominant arm. Muscle soreness, limb girth, plasma creatine kinase (CK) activity, isometric torque and concentric and eccentric torque at 0.52 and 3.14 rad·s-1 were assessed prior to and for several days following the eccentric bout. Peak plasma CK activity was similar in SLW (4030±1029 U·l-1) and FST (5864±2664 U·l-1) groups, (p>0.05). Both groups experienced similar decrement in all strength variables during the 48 hr following the eccentric bout. However, recovery occurred more rapidly in the FST group during eccentric (0.52 and 3.14 rad·s-1) and concentric (3.14 rad·s-1) post-testing. The severity of muscle soreness was similar in both groups. However, the FST group experienced peak muscle soreness 48 hr later than the SLW group (24 hr vs. 72 hr). The SLW group experienced a greater increase in upper arm girth than the FST group 20 min, 24 hr and 96 hr following the eccentric exercise bout. The contraction velocity of an acute bout of eccentric exercise differentially influences the magnitude and time course of several indirect markers of muscle damage.

Original languageEnglish (US)
Pages (from-to)255-263
Number of pages9
JournalJournal of Science and Medicine in Sport
Volume8
Issue number3
DOIs
StatePublished - Sep 2005
Externally publishedYes

Fingerprint

Myalgia
Torque
Creatine Kinase
Muscles
Arm
Elbow
Extremities

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Physical Therapy, Sports Therapy and Rehabilitation
  • Orthopedics and Sports Medicine

Cite this

Differential expression of muscle damage in humans following acute fast and slow velocity eccentric exercise. / Paddon-Jones, Douglas; Keech, A.; Lonergan, A.; Abernethy, P.

In: Journal of Science and Medicine in Sport, Vol. 8, No. 3, 09.2005, p. 255-263.

Research output: Contribution to journalArticle

@article{ac595c6d465b429b9a1f1ecd8d9c2627,
title = "Differential expression of muscle damage in humans following acute fast and slow velocity eccentric exercise",
abstract = "We sought to determine if the velocity of an acute bout of eccentric contractions influenced the duration and severity of several common indirect markers of muscle damage. Subjects performed 36 maximal fast (FST, n=8: 3.14 rad·s-1) or slow (SLW, n=7: 0.52 rad·s-1) velocity isokinetic eccentric contractions with the elbow flexors of the non-dominant arm. Muscle soreness, limb girth, plasma creatine kinase (CK) activity, isometric torque and concentric and eccentric torque at 0.52 and 3.14 rad·s-1 were assessed prior to and for several days following the eccentric bout. Peak plasma CK activity was similar in SLW (4030±1029 U·l-1) and FST (5864±2664 U·l-1) groups, (p>0.05). Both groups experienced similar decrement in all strength variables during the 48 hr following the eccentric bout. However, recovery occurred more rapidly in the FST group during eccentric (0.52 and 3.14 rad·s-1) and concentric (3.14 rad·s-1) post-testing. The severity of muscle soreness was similar in both groups. However, the FST group experienced peak muscle soreness 48 hr later than the SLW group (24 hr vs. 72 hr). The SLW group experienced a greater increase in upper arm girth than the FST group 20 min, 24 hr and 96 hr following the eccentric exercise bout. The contraction velocity of an acute bout of eccentric exercise differentially influences the magnitude and time course of several indirect markers of muscle damage.",
author = "Douglas Paddon-Jones and A. Keech and A. Lonergan and P. Abernethy",
year = "2005",
month = "9",
doi = "10.1016/S1440-2440(05)80036-2",
language = "English (US)",
volume = "8",
pages = "255--263",
journal = "Journal of Science and Medicine in Sport",
issn = "1440-2440",
publisher = "Elsevier BV",
number = "3",

}

TY - JOUR

T1 - Differential expression of muscle damage in humans following acute fast and slow velocity eccentric exercise

AU - Paddon-Jones, Douglas

AU - Keech, A.

AU - Lonergan, A.

AU - Abernethy, P.

PY - 2005/9

Y1 - 2005/9

N2 - We sought to determine if the velocity of an acute bout of eccentric contractions influenced the duration and severity of several common indirect markers of muscle damage. Subjects performed 36 maximal fast (FST, n=8: 3.14 rad·s-1) or slow (SLW, n=7: 0.52 rad·s-1) velocity isokinetic eccentric contractions with the elbow flexors of the non-dominant arm. Muscle soreness, limb girth, plasma creatine kinase (CK) activity, isometric torque and concentric and eccentric torque at 0.52 and 3.14 rad·s-1 were assessed prior to and for several days following the eccentric bout. Peak plasma CK activity was similar in SLW (4030±1029 U·l-1) and FST (5864±2664 U·l-1) groups, (p>0.05). Both groups experienced similar decrement in all strength variables during the 48 hr following the eccentric bout. However, recovery occurred more rapidly in the FST group during eccentric (0.52 and 3.14 rad·s-1) and concentric (3.14 rad·s-1) post-testing. The severity of muscle soreness was similar in both groups. However, the FST group experienced peak muscle soreness 48 hr later than the SLW group (24 hr vs. 72 hr). The SLW group experienced a greater increase in upper arm girth than the FST group 20 min, 24 hr and 96 hr following the eccentric exercise bout. The contraction velocity of an acute bout of eccentric exercise differentially influences the magnitude and time course of several indirect markers of muscle damage.

AB - We sought to determine if the velocity of an acute bout of eccentric contractions influenced the duration and severity of several common indirect markers of muscle damage. Subjects performed 36 maximal fast (FST, n=8: 3.14 rad·s-1) or slow (SLW, n=7: 0.52 rad·s-1) velocity isokinetic eccentric contractions with the elbow flexors of the non-dominant arm. Muscle soreness, limb girth, plasma creatine kinase (CK) activity, isometric torque and concentric and eccentric torque at 0.52 and 3.14 rad·s-1 were assessed prior to and for several days following the eccentric bout. Peak plasma CK activity was similar in SLW (4030±1029 U·l-1) and FST (5864±2664 U·l-1) groups, (p>0.05). Both groups experienced similar decrement in all strength variables during the 48 hr following the eccentric bout. However, recovery occurred more rapidly in the FST group during eccentric (0.52 and 3.14 rad·s-1) and concentric (3.14 rad·s-1) post-testing. The severity of muscle soreness was similar in both groups. However, the FST group experienced peak muscle soreness 48 hr later than the SLW group (24 hr vs. 72 hr). The SLW group experienced a greater increase in upper arm girth than the FST group 20 min, 24 hr and 96 hr following the eccentric exercise bout. The contraction velocity of an acute bout of eccentric exercise differentially influences the magnitude and time course of several indirect markers of muscle damage.

UR - http://www.scopus.com/inward/record.url?scp=27644551357&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=27644551357&partnerID=8YFLogxK

U2 - 10.1016/S1440-2440(05)80036-2

DO - 10.1016/S1440-2440(05)80036-2

M3 - Article

C2 - 16248466

AN - SCOPUS:27644551357

VL - 8

SP - 255

EP - 263

JO - Journal of Science and Medicine in Sport

JF - Journal of Science and Medicine in Sport

SN - 1440-2440

IS - 3

ER -